Results 241 to 250 of about 1,508,019 (309)

Professional bodies: how best to promote and support individuals working in human genetics and genomics. [PDF]

J Hum Genet
Newman WG.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The Motor Neuromuscular Axis: The Overlooked Element of Developmental Programming in Diabetes and Metabolic Syndrome. [PDF]

Int J Mol Sci
Zazula MF, Carvalhal SRS, Maciel DT, Moritz D, Beirauti HYI, Amorim L, Rocha MTD, Maciel M, Sales O, Dobgenski P, Braga P, Banckes TN, Horlem T, Confortim HD, Homem de Bittencourt Júnior PI, Fernandes LC, Naliwaiko K.   +16 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Competition in the brain: a conserved principle with lifespan consequences. [PDF]

Commun Biol
Roy D, Banerjee A.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Operationalising neuroinclusive work systems: A multi-method framework for organisational research. [PDF]

MethodsX
Tootell B, Rao V.
europepmc   +1 more source

Correction: Epitope spreading in multiple sclerosis is shaped by the spatial organisation of immune responses. [PDF]

Front Immunol
Rutkowska A.
europepmc   +1 more source

A three-component dynamical index of consciousness-related neural organisation. [PDF]

Biol Cybern
Ugail H, Howard N.
europepmc   +1 more source

Co-assembly and self-sorting are not mutually exclusive in enantiomeric peptide systems. [PDF]

Chem Sci
Bianco S, Sonani RR, Marshall LJ, Loch AS, Doutch J, Egelman EH, Adams DJ.   +6 more
europepmc   +1 more source