Results 141 to 150 of about 124,566 (258)

Forest administration an example of structural non-uniformity. [PDF]

, 2013
Niniejszy artykuł zwraca uwagę na genezę słowa „administracja” oraz analizuje wartości kształtujące i różnicujące administrację. Zostały przytoczone przykłady na poparcie twierdzeń.
Paradowski, Mariusz, Machoń, Mirosław
core  

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

The Executive Branch: The Government (2) - Comparative Study -

, 2015
The Fundamental Laws of the European Union member states establish the institutional system and also the Government’s organisation. In the present article, after we already studied the organisation of the Chief of State institution, we will analyse
Carausan, Mihaela Victorita; National University of Political Studies and Public Administration, Faculty of Public Administration
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Promoting public managerial sustainability: The relevance of social support for managers in coping with work-related stress

Statistics reveal the concerning prevalence of mental health issues among Swedish public sector managers, highlighting the critical need for deeper insights into the relevance of social support in coping with work-related stress.
Lindén, Magnus, Westrup, Ulrika, Lidén, Alina, Westrup, Ulrika,, Lindén, Magnus,, Lidén, Alina,, Lund University.   +6 more
core   +1 more source

When Ethical Leadership Is Not Enough: A Person-Centred Analysis of Employee Strain and Turnover Intentions. [PDF]

Behav Sci (Basel)
Zehir C, Elbir U, Bıyıklar MA, Balcıoğlu YS.   +3 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source