Results 161 to 170 of about 124,566 (258)

Organisational interventions in nursing care: A scoping review and descriptive system to support comparison. [PDF]

Int J Nurs Stud Adv
Miedema N, Felder M, Stalpers D, van Oostveen C, Rutten-Van Mölken M, Goossens L, RN2Blend consortium.   +6 more
europepmc   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Municipal Organisation 2008, County

This data set is derived from the survey entitled "Municipal Organisation 2008". The survey is conducted by the Norwegian Institute for Urban and Regional Research and was commissioned by the Ministry of Local Government and Regional Development.
Norwegian Institute for Urban and Regional Research
core  

Challenges and enablers of collaborative working in the voluntary, community, social, faith and enterprise sector: impact, effectiveness, and sustainability. [PDF]

Front Public Health
Vincent BP, Ali N, Egbutah C, Perkins K.
europepmc   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

How Did Women From South Asian Backgrounds and People Seeking Asylum and Refugees Look After Their Health and the Health of Others During the COVID-19 Pandemic? A Community Research Approach. [PDF]

Health Expect
Joseph O, Yahya NA, Butt L, Khan A, Khan S, O'Hara JK, Albutt A, Carter R, Haq R, Louch G.   +9 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Municipal Organisation 2008, Municipality

This data set is derived from the survey entitled "Municipal Organisation 2008". The survey is conducted by the Norwegian Institute for Urban and Regional Research and was commissioned by the Ministry of Local Government and Regional Development.
Norwegian Institute for Urban and Regional Research
core  

Irish Travellers' Cancer Awareness and Engagement With Prevention, Screening and Early Diagnosis: A Qualitative Study of Barriers and Enablers. [PDF]

Health Expect
Frazer K, Joye R, Fitzpatrick P, Jalal R, Collins MB, Kavanagh L, Murfitt A, Quirke B, Kennedy U, McCarthy T, McEnery M, Lyng A, Fox P.   +12 more
europepmc   +1 more source