Results 101 to 110 of about 4,643,842 (274)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The Influence of National and Organisational Culture on Creativity in Libyan Work Environments [PDF]

Culture is deemed to be a crucial basis for creativity in various respects. The aim of this study is to explore the relationships between different cultural dimensions, and the work environment for creativity.
Abridah, Alkddafi Ibrahim Altaher
core   +2 more sources

Organisational culture, innovation, and knowledge sharing in selected non-profit organisation projects in South Africa

Cogent Business & Management
This study investigated how organisational culture influences innovation in project-based non-profit organisations (NPOs) in South Africa, with a focus on the mediating role of knowledge sharing. Drawing on the Resource-Based View (RBV) and the Knowledge-
Mareli Swanepoel, William Makumbe, Emmanuel Mutambara   +2 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Humanitarian principles and organisational culture : the case of medecins sans-frontieres, Holland

, 2002
Organisational principles or value standards are considered crucial for maintaining quality in humanitarian assistance. Research among staff members of Médecins Sans Frontières-Holland (MSF-H) showed that fieldworkers construct their own interpretations ...
Hilhorst, Dorothea, Hilhorst, D., Schmiemann, N., Schmiemann, Nadja   +3 more
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Organisational Culture: Reviewing the Conceptual and Importance of Organisational Culture

International Journal of Academic Research in Business and Social Sciences, 2022
Nurul Farhana Nasir, Muhammad Nur Firdaus Nasir, Mutiiah Mohamad, Muhammad Arif Nasir, Shazwani Mohd Salleh, Nor Aizan Mohamed   +5 more
openaire   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Organisational culture in multinational organisations

, 2006
In the last ten years South Africa has seen a dramatic change in the way organisations and individuals, within the business environment, view culture, ethnicity, socio economics, gender and race. These recent developments are largely attributed to globalisation and diverse national and cultural origins.
openaire   +1 more source