Results 91 to 100 of about 4,643,842 (274)

Barriers to organisational change: the role of culture

open access: yes, 1991
First paragraph: Organisational culture has been a recurring theme in the literature on organisations over the last decade. Indeed, it sometimes seems almost impossible to find a book or journal without some reference, albeit often superficial, to the ...
Burnes, B, Burnes, Bernard
core   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Telling Stories: the Link Between Organisational Identity, Culture and Employee Advocacy [PDF]

open access: yes, 2018
Employees who represent the firm to outsiders are a possible advantage of an organisation in the war for talents. Therefore, Employee Advocacy has been identified as important concept.
Zinkstein, K.I.
core   +1 more source

EXPLORING THE ROLE OF INFORMAL ORGANISATIONAL CULTURE ON SERVICE DELIVERY: CASE OF A LOCAL AUTHORITY IN ZIMBABAWE

open access: yesBaltic Journal of Economic Studies
Informal culture, frequently characterised by unwritten rules, social norms and interpersonal relationships, plays a critical role in shaping employee behaviour and organisational effectiveness.
Chenai Mapungwana   +2 more
doaj   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Profiles of organisational culture in Indonesian construction companies [PDF]

open access: yes, 2011
Although relatively few studies have been undertaken analyzing the drivers of performance for construction companies in producing and delivering satisfactory quality of project works, findings from previous research reveal that there is a significant ...
Vaughan Coffey   +5 more
core   +2 more sources

Implementation of quality management in the public sector versus the private sector: a cultural analysis [PDF]

open access: yes, 2009
This thesis reviews the Total Quality Management (TQM) literature and concludes that core to the introduction of TQM in any organisation is a need to be acutely sensitive to the cultural aspects of the organisation.
Butler, John M.J.
core   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Organisational culture for information managers /

open access: yes
"In today's digital environment the workplace is characterised by individuals creating information perhaps independently of formal systems, or establishing new systems without knowledge of information management requirements.
Oliver, Gillian,author.
core  

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