Results 111 to 120 of about 396,912 (271)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Improving patient experience by implementing an organisational culture model. [PDF]
BMJ Open Qual, 2023 Almohaisen NA +6 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Organisational Culture Research in Healthcare: A Big Data Bibliometric Study. [PDF]
Healthcare (Basel), 2023 Qin X +7 more
europepmc +1 more source
A Benchmark for Management Effectiveness [PDF]
This study presents a tool to gauge managerial effectiveness in the form of a questionnaire that is easy to administer and score. The instrument covers eight distinct areas of organisational climate and culture of management inside a company or ...
Bill Zimmermann +2 more
core
The impact of entrepreneurial characteristics and organizational culture on innovativeness in tourism firms [PDF]
, 2015 Entrepreneurial characteristics and organisational culture have an impact on the innovative capability of a company. Therefore, our research tries to examine the influence of different individual entrepreneurial characteristics and organisational ...
Gomezelj Omerzel, Doris
core +2 more sources
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Exploring leadership personality: A key for higher education transformation
Transformation in Higher EducationLeadership plays a critical role in organisational transformation and is strongly shaped by leaders’ personalities and the organisational culture of collective behaviours, attitudes, and values. Literature has indicated that executives’ personalities are
Tessie H.H. Herbst
doaj +1 more source
The influence of the Fourth Industrial Revolution on organisational culture: An empirical investigation. [PDF]
Front Psychol, 2022 Singaram S, Mayer CH.
europepmc +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source