Results 111 to 120 of about 446,896 (309)

The influence of organizational culture on organizational resilience and employee performance through the mediation of high-performance work systems

Discover Psychology
This study investigates the influence of organisational culture (OC) on employee performance (EP) and organisational resilience (OR), as well as the role of high-performance work systems (HPWS) as a mediator.
Shivani Srivastava, M. K. Rao
doaj   +1 more source

Human Resource management, Institutionalisation and Organisational Performance [PDF]

The relationship between Human Resource Management (HRM) and firm performance has been a hotly debated topic over the last decade, especially in the United States (e.g. Osterman, 1994; Huselid, 1995; MacDuffie, 1995).
Boselie, J.P.E.F., Paauwe, J., Richardson, R.   +2 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Organisational structures and integrated care. An evaluation of interventions in ten care organisations

International Journal of Integrated Care, 2015
Sam Pless, Lander Vermeerbergen, Ezra Dessers, Geert Van Hootegem   +3 more
doaj   +3 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Knowledge management and organisational performance: a literature review [PDF]

Although knowledge management is considered as a very recent phenomenon, research in to knowledge and the management of the knowledge within the business context has grown dramatically over the last few years, in a number of different directions.
Amaratunga, Dilanthi, Haigh, Richard, Pathirage, C. P.   +2 more
core  

Dynamic Capabilties and Organisational Performance [PDF]

, 2007
This paper presents a conceptual framework for the dynamic capabilities organisational performance relationship. It implies that the organisational resource-base (e.g.
Gudergan, S, Lings, IN, Wilden, RM
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Impact of contextual factors on organisational performance mediated by talent management

SA Journal of Industrial Psychology
Orientation: Talent management has become a significant concept in human resource management because of the potential influence thereof on organisational performance in a competitive business environment.
Gladys B. Zake, Petronella Jonck, Anna-Marie Pelser   +2 more
doaj   +1 more source

Studying Organisational Topology with Simple Computational Models [PDF]

The behaviour of many complex systems is influenced by the underlying network topology. In particular, this applies to social systems in which people or organisational units collaboratively solve problems.
Anthony Dekker
core