Results 131 to 140 of about 378,729 (334)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Omul în organizația sa

open access: yesRevista Transilvană de Ştiinţe Administrative, 2003
We see how, currently, people are involved in many organisational forms by their choice. They seem to enjoy this way of work because there is a possibility to have a word to say.
Mirela PINTE
doaj  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Observation and shadowing: Two methods to research values and values work in organisations and leadership. Kap. 8

open access: yes, 2022
This open access book presents new approaches for researching values as they are performed or materialized. Values have been an important topic in academic literature for a long time; they are at the core of institutional theories and are often connected to ideals in organisations or ways of valuing.
Sirris, Stephen   +2 more
openaire   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Kesediaan pelajar politeknik kejuruteraan elektrik dalam menceburi bidang keusahawanan [PDF]

open access: yes, 2012
Bidang keusahawanan kini semakin berkembang maju selaras dengan seruan kerajaan yang banyak memberi dorongan kepada rakyat Malaysia agar menjadikan usahawan sebagai kerjaya utama. Kajian yang dijalankan adalah untuk mengenal pasti kesediaan pelajar
Mohd Halid, Nurul Nadhilah
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Research note: Complying with frustration, the experience of equality and diversity practitioners [PDF]

open access: yes, 2015
The Equality and Diversity (E&D) role in Higher Education (HE) in the UK ensures that universities are compliant with equalities legislation and that they fulfil their duty to promote equality as these relate to employees and the institution as a whole ...
Joy, Simy   +3 more
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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