Results 31 to 40 of about 803,924 (317)

Anatomy of life and well-being: A framework for the contributions of phenomenology and complexity theory

open access: yesInternational Journal of Qualitative Studies on Health & Well-Being, 2010
This paper proposes an anatomy of the phenomena of life and of correlate qualitative modes of empirical research, theory, and professional practice concerned with health and well-being.
Robert Mugerauer
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Disentangling the Holism of Intentional Systems From the Interactionism of Mechanistic Systems in Person-Oriented Research

open access: yesJournal for Person-Oriented Research, 2015
A key assumption in the person-oriented approach is that a person must be understood as a complex, integrated system, represented by patterns of within-person variation rather than scores on separate variables.
Artur Nilsson
doaj   +1 more source

Midbrain Dopamine Neurons Defined by TrpV1 Modulate Psychomotor Behavior

open access: yesFrontiers in Neural Circuits, 2021
Dopamine (DA) neurons of the ventral tegmental area (VTA) continue to gain attention as far more heterogeneous than previously realized. Within the medial aspect of the VTA, the unexpected presence of TrpV1 mRNA has been identified.
Gian Pietro Serra   +4 more
doaj   +1 more source

Social Movements: Organizations and Organizing

open access: yes, 2017
We discuss two lines of research that emerged at the crossroads of social movement studies and organization theory, focusing on organizations and organizing, respectively. We speak of ‘organizations’ and ‘organizing’ to emphasize that the ‘social movement/organizations’ nexus is distinct from the ‘social movement/organizing’ nexus.
de Bakker, Frank   +2 more
openaire   +4 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Biological age and rates of senescence of organism of students [PDF]

open access: yesPedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2010
Correlations of biological and passport age of student young people are considered. In an experiment took part 25 students by age 17-19 years. The calculation of their biological age is conducted.
Loshits'ka T.I.
doaj  

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Engineering a DYRK1B R102C mutation: insights into metabolic syndrome pathogenesis through lentiviral gene delivery [PDF]

open access: yesMedical Laboratory Journal
Background: A rare heterozygous DYRK1B mutation (R102C) recently linked to a familial form of metabolic syndrome prompted this study to introduce the R102C mutation into the mouse DYRK1B gene, utilizing recombinant lentiviruses for long-term gene ...
Afrooz Daneshparvar   +6 more
doaj  

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

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