Results 131 to 140 of about 826,626 (298)

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

EDAD 621 Foundations of School Administration & Organization

, 2003
Course syllabus for EDAD 621 Foundations of School Administration & Organization Course description: Introduction to the study of educational administration with emphasis upon the nature of the administrative process, administrative theory, and long ...
Alexander, Diane
core   +1 more source

Trabalhando a missão de um hospital como facilitador da mudança organizacional: limites e possibilidades

Cadernos de Saúde Pública
O autor, inicialmente, apresenta algumas considerações encontradas no campo da Teoria Geral da Administração, sobre o papel da definição de "objetivos organizacionais" em um processo de mudança das organizações em geral.
Luiz Carlos de Oliveira Cecilio
doaj  

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Os fatores determinantes da rotatividade externa dos enfermeiros: vínculo contratual, incentivos salariais ou reconhecimento profissional Los factores determinantes de la rotatividad externa de los enfermeros: vínculo contractual, incentivos salariales o reconocimiento profesional The main determinants of nursing turnover: contractual obligation, wage benefits or professional recognition

Revista de Enfermagem Referência, 2011
Nos últimos anos as organizações de saúde, a profissão e a carreira de enfermagem sofreram um conjunto de alterações estruturais, processuais e políticas.
Ana Poeira, Ricardo Paes Mamede
doaj  

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Administrative Organization.

American Sociological Review, 1961
Amitai Etzioni, J. M. Pfiffner, F. P. Sherwood   +2 more
openaire   +2 more sources

Investigation of the Effects of Calendula officinalis on Gingival Tissue in Streptozotocin-Induced Diabetic Rats. [PDF]

Cureus
Tekbas I, Yalcin B, Bozgeyik E, Calisir M.   +3 more
europepmc   +1 more source