Results 151 to 160 of about 826,626 (298)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Etiology and incidence of diarrhea requiring hospitalization in children under 5 years of age in 31 low- and middle-income countries: Findings from the Global Pediatric Diarrhea Surveillance network, 2017-2022. [PDF]

PLOS Glob Public Health
Soeters HM, Antoni S, Iyer SS, Weldegebriel G, Biey J, Mwenda JM, Rey-Benito G, Ortiz C, Pastore R, Videbaek D, Singh S, Njambe E, Sangal L, Dhongde D, Grabovac V, Logronio J, Fahmy K, Ghoniem A, Armah G, Dennis FE, Seheri ML, Magagula N, Rakau-Nondela K, Fumian TM, Maciel ITA, Samoilovich E, Semeiko G, Varghese T, Thomas S, Bines JE, Li D, Kabir F, Liu J, Houpt ER, Gautam R, Mirza SA, Vinjé J, Mulders MN, Tate JE, Parashar UD, Platts-Mills JA, Global Pediatric Diarrhea Surveillance network.   +41 more
europepmc   +1 more source

Annual report 1995 - North Pacific Marine Science Organization (PICES). Fourth meeting, Qingdao, People's Republic of China, October 16-24, 1995

, 1996
Report of Opening Session Report of Governing Council Meetings Reports of Science Board and Committees: Science Board Biological Oceanography Committee Fishery Science Committee Marine Environmental Quality Committee Physical Oceanography and Climate ...

core  

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Histological Effects of PRP and Corticosteroids Following In Situ Repair of Bursal-Sided Partial Rotator Cuff Tears: An Experimental Rat Study. [PDF]

Biomedicines
Kaya AÖ, Akalın Y, Çevik N, Çetin O, Türkmensoy F, Avci Ö, Öztürk A.   +6 more
europepmc   +1 more source

Report to the President for year ended June 30, 2024, Research Administration Services

This report contains the following sections: About Research Administration Services (RAS), The RAS Organization, Key Challenges, Federal negotiations team pilot, and Summary and goals for the ...
Holmes, Vivian
core  

Annual report 1993 - North Pacific Marine Science Organization (PICES). Second meeting, Seattle, WA, U.S.A., October 25-30, 1993

, 1994
Report of Opening Session Report of Governing Council Meetings Reports of Science Board and Committees: Science Board Biological Oceanography Committee Fishery Science Committee Marine Environmental Quality Committee Physical Oceanography and Climate ...

core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Inhibition of CDK/Cyclin-phospho-Rb signaling by amebaciclib may have an antitumor effect against uterine leiomyosarcoma. [PDF]

Signal Transduct Target Ther
Hayashi T, Muto M, Konishi I.
europepmc   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source