Results 151 to 160 of about 730,203 (311)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Unified planning work program federal fiscal year 2008 [PDF]

3C PL Contract 48696Contract MA-80-001This Unified Planning Work Program (UPWP) contains information about surface-transportation planning projects that will be conducted in the Boston metropolitan region during the period of October 1, 2007, through ...
Boston Metropolitan Planning Organization, United States. Federal Highway Administration, United States. Department of Transportation. Federal Transit Administration   +2 more
core  

AI-Integrated Counseling Administration Quality and Organizational Support as Drivers of Early Risk Detection in Indonesian Schools. [PDF]

F1000Res
Novebri N, Kurniady DA, Komariah A, Sianturi R, Kadarsah D, Tamam B, Kusumadewi RA, Darmawan D, Akil A, Hadiyanto H.   +9 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

ORGANIZATION OF PUBLIC ADMINISTRATION

, 2012
V diplomski nalogi z naslovom Organiziranje javne uprave sem s pregledom domače in tuje literature raziskovala področje javne uprave. Za to temo sem se odločila, ker me je zanimalo področje javne uprave. Tema se mi je zdela aktualna v tem obdobju.
Gruškovnjak, Natalija
core  

Transition from Parenteral to Subcutaneous Application of Systemic Oncological Therapy for Treating Non-Small-Cell Lung Cancer. [PDF]

Curr Oncol
Muratovic A, Janzic U.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Ordering Things: The Irish State Administration Database [PDF]

New theoretical approaches to the state have posed challenges for the comparative analysis of the organizational features of states. The analysis of state bodies and state agencies has largely been confined to the sub-discipline of public administration,
Colin Scott, Niamh Hardiman
core  

Multiscale imaging of polarity in bovine oviductal organoids. [PDF]

Front Cell Dev Biol
Dunn B, Meyers MA, Burlingham S, Morisaki T, Darehshouri A, Gad A, Thompson-Brandhagen R, Stasevich TJ, Hollinshead FK.   +8 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source