Results 141 to 150 of about 730,203 (311)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Trabalhando a missão de um hospital como facilitador da mudança organizacional: limites e possibilidades

Cadernos de Saúde Pública
O autor, inicialmente, apresenta algumas considerações encontradas no campo da Teoria Geral da Administração, sobre o papel da definição de "objetivos organizacionais" em um processo de mudança das organizações em geral.
Luiz Carlos de Oliveira Cecilio
doaj  

Improved triage and emergency care for children reduces inpatient mortality in a resource-constrained setting

Bulletin of the World Health Organization, 2006
PROBLEM: Early assessment, prioritization for treatment and management of sick children attending a health service are critical to achieving good outcomes.
Molyneux Elizabeth, Ahmad Shafique, Robertson Ann   +2 more
doaj  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Southern Business Administration Association Records - Accession 683

The Southern Business Admission Association Records consists of bylaws and constitution, financial records, membership records, correspondence, minutes, papers relating to meetings, and history relating to the Southern Business Administration Association
Southern Business Administration Association
core  

Development administration in the United Arab Emirates : a socio-political approach [PDF]

This study is concerned with the United Arab Emirates (U.A.E.) development administration with particular emphasis on the effect of its social and cultural features on its bureaucracy and indigenous civil servants.
Jakka, Ateeq Abdul-Aziz
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Personnel administration of Schools under Khon Kaen Provincial Administration Organization

การวิจัยครั้งนี้มีวัตถุประสงค์เพื่อ 1) ศึกษาการบริหารงานบุคคลของสถานศึกษาสังกัดองค์การบริหารส่วนจังหวัดขอนแก่น และ (2) เปรียบเทียบการบริหารงานบุคคลของสถานศึกษาสังกัดองค์การบริหารส่วนจังหวัดขอนแก่น จำแนกตามขนาดสถานศึกษา กลุ่มตัวอย่าง คือ ครูในสถานศึกษาส ...
ปิยะนุช ทีทา
core  

U.S. Fuel Trends Analysis and Comparison to GIACC/4-IP/1 [PDF]

Project 28 is funded by the Federal Aviation Administration and the U.S. Air Force Research Laboratory. Citation:International Civil Aviation Organization/Group on International Aviation and Climate Change (ICAO/GIACC), 2009.
Group on International Aviation and Climate Change (GIACC)), International Civil Aviation Organization   +1 more
core  

The importance of focusing on entomology in the efforts to eliminate onchocerciasis. [PDF]

Int Health
Tallant J, Mackenzie CD, Boakye D, Heggen A, Leff S, Gatawa E, Zongo K, Mberu M, Albrieux P.   +8 more
europepmc   +1 more source