The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Nurses' Perceptions and Experiences of Unethical Pro-Organizational Behavior: A Descriptive Qualitative Study. [PDF]
Li Y +10 more
europepmc +1 more source
Role of corporate social responsibility, management practices, organizational behavior in social equity with mediating role of women empowerment: A study of the Islamic banking sector of South Punjab. [PDF]
Basheer MF +4 more
europepmc +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
The effect of servant leadership on medical staff unethical pro-organizational behavior: the role of work meaning and power distance. [PDF]
Zeng J, Cai J, Li L, Yang Q.
europepmc +1 more source
Is Anyone Else Feeling Completely Nonessential? Meaningful Work, Identification, Job Insecurity, and Online Organizational Behavior during a Lockdown in The Netherlands. [PDF]
Ouwerkerk JW, Bartels J.
europepmc +1 more source
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Retraction: Characteristics and trends in unethical pro-organizational behavior research in business and management: a bibliometric analysis. [PDF]
Frontiers Editorial Office.
europepmc +1 more source

