Results 151 to 160 of about 6,765,960 (292)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Comprehensive trauma-informed organizational change at an academic medical center in South Texas. [PDF]

BMC Health Serv Res
Sebton SA, Bridger CM, Arias PA, Okeibunor CK, Spencer SR, Willis RE, Taylor SE, Alsip BJ.   +7 more
europepmc   +1 more source

Unravelling the relationship between perceived values-congruence with organizational change readiness: A moderated mediation model. [PDF]

Front Psychol, 2023
Deng J, Cheng Z, Qi S, Deng R.
europepmc   +1 more source

Surviving Organizational Change

Nursing Management (Springhouse), 1990
openaire   +3 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Research on supply chain resilience mechanism of AI-Enabled manufacturing enterprises -based on organizational change perspective. [PDF]

Sci Rep
Guo X, Chen Y, Xie J, Wang H, Lei X.
europepmc   +1 more source

Measuring the Organizational Change Maturity of Chilean Companies. [PDF]

Front Psychol, 2021
Mac Carte P, Fariña P.
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Healthcare workers' readiness for artificial intelligence and organizational change: a quantitative study in a university hospital. [PDF]

BMC Health Serv Res
Boyacı H, Söyük S.
europepmc   +1 more source

Strengthened through Diversity: A Blueprint for Organizational Change. [PDF]

Ann Neurol, 2021
Willis A, Skolarus LE, Faigle R, Menon U, Redwine H, Brown AM, Felton E, Mendizabal A, Nath A, Jensen F, McArthur JC.   +10 more
europepmc   +1 more source