Results 231 to 240 of about 1,224,570 (272)

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

Advanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen, Xinhui Zheng, Jieliu Li, Minyu He, Dongqi Fan, Xingyu Zhu, Qiming Zhai, Liangjing Xin, Tao Chen   +8 more
wiley   +1 more source

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

Acceptance of Digital Technology Among Nursing Staff in Geriatric Long-Term Care: Systematic Review. [PDF]

JMIR Nurs
Iseni J, Swoboda W, Houben D, Hilla R.
europepmc   +1 more source

Intelligent employee behavior analysis for organizational culture optimization with q rung orthopair fuzzy FUCA. [PDF]

Sci Rep
Wang L, He C.
europepmc   +1 more source

Nurses' perspectives on emergency room healthcare constraints in implementing family-centered care: A qualitative study in Indonesia. [PDF]

Belitung Nurs J
Rakhmawati W, Mufida, Mediani HS, Fitri SYR, Mardhiyah A, Rhamelani P.   +5 more
europepmc   +1 more source

Mapping digital transformation and social impact in Italian healthcare: a holistic evaluation of organizational digital maturity. [PDF]

BMC Health Serv Res
Galdiero C, Marrapodi R, Mele S, Scaletti A, Martinez M.   +4 more
europepmc   +1 more source

Exploring nurses' experiences and perceptions of mentorship programs in Riyadh, Saudi Arabia: an interpretive phenomenological analysis. [PDF]

BMC Nurs
Alshehri WM, Alodhailah AM.
europepmc   +1 more source

Workplace Loneliness Experience Among Older Professionals (Aged ≥50 Years) in the Context of Digitalization: Protocol for a Scoping Review.

JMIR Res Protoc
Țânculescu-Popa LI, Piedade Brandão M, Aksoy Ş, Pessoto Hirata R, Ilgaz A, Tofan CM.   +5 more
europepmc   +1 more source