Results 61 to 70 of about 1,178,077 (288)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Towards Design Principles for Data-Driven Decision Making: An Action Design Research Project in the Maritime Industry [PDF]

, 2018
Data-driven decision making (DDD) refers to organizational decision-making practices that emphasize the use of data and statistical analysis instead of relying on human judgment only.
Müller, Oliver, Thiess, Tiemo
core   +1 more source

Professional desire, competence and engagement in IS context [PDF]

, 2009
This paper attempts to address the failings of a predominant paradigm in IS research and practice that emphasises technological determinism. This paradigm makes use of a false belief in the power of rationality in organizational decision-making, and a ...
Bednar, Peter, Welch, Christine
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Title: A study of the relationship between managers\' decision making styles and organizational health in Isfahan University of Medical Sciences

Salāmat-i kār-i Īrān, 2012
Background and Aims: Managers decision making style can function effectively correct departments in universities and its positive impact on organizational health group will increase efficiency.
S Bahrami, S Rajaeepour, M Keyvanara, A.R Raesei, I Kazemi   +4 more
doaj  

The Effect of Knowledge Management on Nonfinancial Functions of Financial Organizations through the Moderating Role of Decision Making Styles [PDF]

مدیریت راهبردی دانش سازمانی, 2019
Given the new approaches to the information age regarding the critical position of knowledge management and decision making strategies in organizations, this study focuses on the procedural implications of knowledge management, discussing their role in ...
Rouhollah Tavallaei, Zeinab Karimi, Navid Nezafati   +2 more
doaj  

The Optimal Design of Fallible Organizations: Invariance of Optimal Decision Criterion and Uniqueness of Hierarchy and Polyarchy Structures [PDF]

We present a general framework to study the project selection problem in an organization of fallible decision-makers. We show that when the organizational size and the majority rule for project acceptance are optimized simultaneously, the optimal quality
Winston T H Koh
core  

Organizational Aspects of Multicriteria Decision Making [PDF]

, 1980
Decision making processes include organizational or institutional aspects in which human judgement and reflection of the decision maker are formed. Thus, analysis of organizational behaviors in the decision making processes has been attracting increasing
Seo, F.
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source