Results 61 to 70 of about 155,400 (311)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Journal of Modern ScienceObjectives Article presents management functions in the context of organizational decision-making. Organizational management functions are the fundamental areas of managerial activity, allowing them to direct the work of people and resources to achieve ...
Marcin Stencel +3 more
doaj +1 more source
The impact of perceived organizational cronyism on decision-making: The moderating role of ethical organizational culture [PDF]
Problems and Perspectives in ManagementOne of the primary responsibilities of managers is to make informed decisions that promote company progress and enhance performance. Unfortunately, not all managers adhere to appropriate decision-making standards.
Hamza Khraim
doaj +1 more source
, 2006 This thesis critically assesses the literature on strategic management accounting that is budgeting and corporate governance and also the managerial decision-making literature (primarily in the areas of strategic planning and change management).
Holloway, David
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
The analysis of the capacity of the selected measures of decision-making models in companies
Copernican Journal of Finance & Accounting, 2015 The paper aims at the analysis of the information capacity of selected instruments of the assessment of decision-making models in the analyzed companies. In the paper there are presented the idea and concepts of decision-making models.
Helena Kościelniak +3 more
doaj +3 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
AI-Driven Decision-Making in the Egyptian Banking Sector: The Mediating Role of Decision-Making Efficiency [PDF]
المجلة العربية للإدارةThe purpose of this study is to assess the impact of artificial intelligence (AI) capabilities on strategic planning and execution in the Egyptian banking sector.
Amira Omar
doaj +1 more source
Dynamic utilisation of knowledge in decision making [PDF]
The contribution of this research is a set of novel insights on the interplay of knowledge assets during decision making. Knowledge is conceptualised as a dynamic resource.
Soskic, Nevena
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source