Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Artificial Intelligence and Human Resource Management: A Counterfactual Analysis of Productivity
This study explores how industrial firms could have achieved stronger competitive performance if artificial intelligence–driven human resource management (AI-HRM) practices had existed during earlier stages of industrial production. The central objective
Geoffrey Ditta
doaj +1 more source
The Impact of the New Information and Communication Technologies on the Performance Control Indicators System [PDF]
Our paper emphasizes the way in which the information and communication technologies offer a real support to the managers which have a global vision on the key factors that assure business performances.
Adriana OLARU, Alexandru CAPATINA
core
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
This study aimed to analyze the impact of the use of ERP systems on organizational efficiency and effectiveness and inter-organizational efficiency of small and medium enterprises in Patos de Minas County. Using a survey adapted from Saccol et al. (2004),
Renato Borges Fernandes +3 more
doaj +1 more source
Barriers to energy efficiency improvement: Empirical evidence from small-and-medium sized enterprises in China [PDF]
This paper analyzes barriers for energy efficiency investments for small-and medium-sized enterprises (SMEs) in China. Based on a survey of 480 SMEs in Zhejiang Province, this study assesses financial, informational, and organizational barriers for ...
Andreas, Jan G. +2 more
core
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Technical efficiency evaluation of military hospitals in Iran using data envelopment analysis [PDF]
Background: Healthcare costs in our economies have grown dramatically in the past few decades where inefficiency in healthcare operations has contributed to these rising costs.
mehdi sadidi +3 more
doaj
PERFORMANCES AND EFFICIENCIES OF THE IRRIGATION WATER USERS’ ASSOCIATIONS IN TUNISIA [PDF]
This article analyzes the efficiency of Water Users Associations (WUA) in the Cap Bon region (Tunisia) and studies its main determinants. The analysis is performed in two stages.
Buysse, Jeroen +4 more
core +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source

