Results 61 to 70 of about 770,724 (307)
Externalities, Communication and the Allocation of Decision Rights [PDF]
, 2005 This paper views authority as the right to undertake decisions that impose externalities on other members of the organization. When only decision rights can be contractually assigned to one of the organization’s stakeholders, the optimal assignment ...
Bester, Helmut
core +4 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Some determinants of organizational success [PDF]
Organizational efficiency and productivity determined by variables associated with economics, psychology, and ...
Becker, S. W., Stafford, F.
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
The impact of intellectual capital on ROA as a significant indicator of financial performance
BizInfoIn the modern business, organizations that recognize the value of intellectual resources and incorporate them into their business strategy have a greater chance of long-term success.
Ana Urosević +2 more
doaj +1 more source
Ingeniería Industrial, 2014 Las empresas utilizan Lean Thinking como filosofía para eliminar desperdicios. Asimismo, CRM es una estrategia de negocio para mejorar la relación con los clientes, aunque su potencial no se ha desarrollado completamente.
Joseph-Robert Voelkl-Peñaloza +3 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
What Do We Know About the Economic Efficiency of Cooperatives: An Evaluative Survey [PDF]
A debate has arisen concerning the economic efficiency of cooperatives relative to other organizational forms. This paper discusses the efficiency concepts and economic theory relevant to the debate and then proceeds to study the empirical evidence.
Iskow, Julie, Sexton, Richard J.
core +1 more source
Towards Data Protection Compliance [PDF]
, 2010 Privacy and data protection are fundamental issues nowadays for every organization. This paper calls for the development of methods, techniques and infrastructure to allow the deployment of privacy-aware IT systems, in which humans are integral part of ...
Etalle, Sandro +2 more
core +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source