Results 161 to 170 of about 1,287,348 (311)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Assessing organizational health literacy in hospitals by using the International Self-Assessment Tool for Organizational Health Literacy of Hospitals - a feasibility study in six European countries. [PDF]

BMC Health Serv Res
Straßmayr C, Finbråten HS, Bitzer EM, Bonaccorsi G, Cacciuttolo MG, Dudra J, Guttersrud Ø, Islertas Z, Jeitani C, Krajnović D, Le C, Levin-Zamir D, Lombardo C, Lorini C, Marcozzi B, Palmieri L, Schütze D, Specchia ML, Šteflová A, Stević I, Struk P, Unim B, Van den Broucke S, Zanobini P.   +23 more
europepmc   +1 more source

Health literacy at work - individual and organizational health literacy, health supporting leadership and employee wellbeing. [PDF]

BMC Health Serv Res, 2023
Lindert L, Choi KA, Pfaff H, Zeike S.
europepmc   +1 more source

The Impact of Leadership on Health – A Preliminary Discussion [PDF]

Contemporary leaders are confronted with unrelenting demands while setting visions, goals, and objectives for organizations. Empirical studies have shown that leaders are increasingly faced with high levels of stress which, in turn, have an impact on the
Franco GANDOLFI
core  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Do Nurses Thrive in Their Organization? Validation of the Short Form of Nurses' Organizational Health Questionnaire. [PDF]

Nurs Rep
Sili A, De Maria M, Della Bella V, Fiorini J, Barbaranelli C.   +4 more
europepmc   +1 more source

Organizational Health Literacy and Health Among New York State Medicaid Members. [PDF]

Health Lit Res Pract, 2023
Robertson TW, Manganello JA, Wu M, Miller LS, Yucel RM, Schettine AM.   +5 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Digital transformation in organizational health and safety to mitigate Burnout Syndrome. [PDF]

Front Public Health, 2023
Sanchez-Segura MI, Dugarte-Peña GL, Medina-Dominguez F, Amescua Seco A, Menchen Viso R.   +4 more
europepmc   +1 more source