Results 171 to 180 of about 12,897,923 (309)

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Strengthening the organizational health literacy capacity of community-based organizations to support COVID-19 precautionary behaviors in marginalized communities. [PDF]

Front Public Health
Fleary SA, LaMonica M, Van Troy-Duran H, Parrella K.   +3 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Use of machine learning for fraud detection within the claims management process in the Philippines: insights from the national health insurance scheme PhilHealth

vii, 19 p.This report examines the use of machine learning (ML) for fraud detection within the claims management process of the Philippine Health Insurance Corporation (PhilHealth), the agency responsible for implementing the country’s national health ...
World Health Organization
core  

United Kingdom (Scotland): health system review

, 2012
xxii, 150 p.Over the last decade, Scotland’s health system has increasingly diverged from the health system in England. Scotland has pursued an approach stressing integration and partnership among all parts of its NHS as opposed to an English approach in
European Observatory on Health Systems and Policies, Steel, David, World Health Organization. Regional Office for Europe, Cylus, Jonathan   +3 more
core  

Enhancing organizational health literacy through pediatric clinical training: Mini-CEX-based formative assessment in case-based learning for pediatric pneumonia-a perspective. [PDF]

Front Public Health
Ge SN, Li B, Mu BY, Wan LS.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Assessing organizational health literacy in hospitals by using the International Self-Assessment Tool for Organizational Health Literacy of Hospitals - a feasibility study in six European countries. [PDF]

BMC Health Serv Res
Straßmayr C, Finbråten HS, Bitzer EM, Bonaccorsi G, Cacciuttolo MG, Dudra J, Guttersrud Ø, Islertas Z, Jeitani C, Krajnović D, Le C, Levin-Zamir D, Lombardo C, Lorini C, Marcozzi B, Palmieri L, Schütze D, Specchia ML, Šteflová A, Stević I, Struk P, Unim B, Van den Broucke S, Zanobini P.   +23 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Multi-staged development and pilot testing of a self-assessment tool for organizational health literacy. [PDF]

BMC Health Serv Res, 2023
Klockmann I, Jaß L, Härter M, von dem Knesebeck O, Lüdecke D, Heeg J.   +5 more
europepmc   +1 more source