Results 181 to 190 of about 778,544 (330)
Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
FEBS Open Bio, EarlyView.Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
Organizational identity, employee's organizational identification and well-being
, 2015 Purpose: The topic of identity has developed primarily around the concept of organizational identity (emphasizing the role of internal processes in defining a collective and shared understanding of the distinctive values of an organization: e.g., Albert & Whetten, 1985), and the personal-level construct of organizational identification (a perceived ...
DI STEFANO, Giovanni, SPATA, Pietro
openaire +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
The Impact of Job Insecurity on Knowledge-Hiding Behavior: The Mediating Role of Organizational Identification and the Buffering Role of Coaching Leadership. [PDF]
Int J Environ Res Public Health, 2022 Jeong J, Kim BJ, Kim MJ.
europepmc +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
How Narcissistic Leaders Impact on Subordinate's Followership During the COVID-19? The Moderating Role of Organizational Identification. [PDF]
Front Psychol, 2022 Wang L, Guo Q.
europepmc +1 more source
Perceived external prestige, organizational identification and organizational commitment
, 2011 Prispevek obravnava odnos med skupinsko in korporacijsko identifikacijo, zaznanim eksternim prestižem in zavezanostjo organizaciji s strani zaposlenih. Rezultati študije kažejo, da zaznani eksterni prestiž povečuje korporativno identifikacijo in pripomore k pojasnitvi organizacijske zavezanosti.
openaire +2 more sources
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source