Intra-organizational integration and innovation: organizational structure, environmental contingency and R&D performance [PDF]
It is widely thought that intra-firm integration has a positive effect on organizational performance, especially in environments characterized by complex and uncertain information. However, counter arguments suggest that integration may limit flexibility
John P. Walsh, You-Na Lee
core
Reviewing the relationship between organizational performance, dynamic capabilities and strategic behavior. [PDF]
SN Bus Econ, 2023 Drago HF +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Perceived organizational support, organizational cynicism and employee well-being [PDF]
, 2014 The present study examined how an employee’s perception of their employing organization can impact his or her thoughts, feelings and behaviors. This study examined cognitive, affective and behavioral organizational cynicism in relation to perceived ...
Peplinski, Marin Sara
core
Impact of knowledge management on job satisfaction and organizational performance among healthcare employees: A structural equation modeling approach. [PDF]
Health Sci Rep, 2023 Fadaie N, Lakbala P, Ghanbarnejad A.
europepmc +1 more source
Astrocyte heterogeneity in brain metastases
Molecular Oncology, EarlyView.Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
Cultivating organizational performance through the performance measurement systems: Role of psychological empowerment and creativity. [PDF]
Front Psychol, 2023 Zhang L, Kim D, Ding S.
europepmc +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Associations Among Organizational Capabilities, Organizational Performance and the Medical Alliance Implementation Effect in Community Health Centers in China: A Moderated Mediation Model. [PDF]
Risk Manag Healthc Policy, 2023 Cui C, Lv B, Meng K.
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source