Results 101 to 110 of about 91,350 (314)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Competency-Based Training of Managers in the Iranian Ministry of Health and Medical Education

مدیریت اطلاعات سلامت, 2012
Background: In every organization, productivity is considerably related with organizational knowledge, experience, creativity, and skills. Therefore, an organization must develop training programs to extract and supply individual, occupational, and ...
Mohammad Hossein Salarianzadeh, Mahdi Jafari Sirizi, Mohammad Hossein Yarmohammadian, Ali Maher   +3 more
doaj  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

About directions of overcoming of the modern crisis States of the economy of Russia

Вестник университета, 2016
In the general methodical plan the offer on the organisation of system of the indicative analysis and regulation of volumes of output is proved and reveals and is industrial-economic activities the enterprises and the organisations of real sector of ...
V. Serov, N. Moiseenko
doaj  

DEFINITION OF THE FUNCTIONAL-PLANNING ORGANIZATION OF THE RESIDENTIAL BUILDING AREA IN COMPLEX REGULATORY DOCUMENTS

, 2022
Svitlana Topal, Oleksandra Synhayivska
openalex   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

GENDER-SENSITIVE CORRELATION BETWEEN COMMUNICATION AND ORGANIZATIONAL SKILLS WITH PROFESSIONAL EFFECTIVENESS OF MANAGERS

RUDN Journal of Psychology and Pedagogics, 2016
The paper discusses the problem of gender-sensitive correlation between the communicative and organizational skills and the professional performance of managers in commercial organization.
N V Obidina
doaj  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

About directions of overcoming of the modern crisis States of the economy of Russia

Вестник университета, 2019
In the general methodical plan the offer on the organisation of system of the indicative analysis and regulation of volumes of output is proved and reveals and is industrial-economic activities the enterprises and the organisations of real sector of ...
V. Serov, N. Moiseenko
doaj