Results 121 to 130 of about 8,514,639 (349)

Rural Alaska Corrections Plan (A Summary) [PDF]

open access: yes, 1980
Efforts to improve correctional services in the rural, predominantly Native communities of Alaska have been going on since before statehood. Complete implementation of plans developed by the Alaska Criminal Justice Planning Agency during the 1970s have ...
Angell, John E.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Commercialization of the land remote sensing system: An examination of mechanisms and issues [PDF]

open access: yes
In September 1982 the Secretary of Commerce was authorized (by Title II of H.R. 5890 of the 97th Congress) to plan and provide for the management and operation of the civil land remote sensing satellite systems, to provide for user fees, and to plan for ...
Cauley, J. K.   +4 more
core   +1 more source

Project Management For Developing Countries: Back to Basics [PDF]

open access: yes, 2017
This article has been on ways by which developing countries can go back to the basics of project management as a means for developmental goals. Project management has proven to be an effective and flexible management approach, which has the potential of ...
Asare, Adams Bediako
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Roles in construction projects: analysis and terminology [PDF]

open access: yes, 2001
Standard form contracts are typically developed through a negotiated consensus, unless they are proffered by one specific interest group. Previously published plans of work and other descriptions of the processes in construction projects tend to focus on
Hughes, Will   +2 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Organizational procedures more used in the classes of sport

open access: yesCultura Física y Deportes de Guantánamo, 2019
In the planning of the sport class it plays an indispensable paper the organizational procedures. In the Sport Cocktail "Prince", county Havana deficiencies were detected in the methodological visits carried out to the classes: bad use of the ...
Grettel Polo-Bugallo   +2 more
doaj  

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Competency-Based Training of Managers in the Iranian Ministry of Health and Medical Education

open access: yesمدیریت اطلاعات سلامت, 2012
Background: In every organization, productivity is considerably related with organizational knowledge, experience, creativity, and skills. Therefore, an organization must develop training programs to extract and supply individual, occupational, and ...
Mohammad Hossein Salarianzadeh   +3 more
doaj  

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