Results 101 to 110 of about 8,514,639 (349)
ORGANIZATIONAL IMPROVEMENT PLAN [PDF]
, 2018 Within the constraints of competing ideologies; Indigenous vs Western knowledge, health service leaders committing to embedding cultural safety and humility into health care services for Indigenous peoples, and the broader change of direction laid out by the Truth and Reconciliation Commission of Canada (2015), is the overall need to improve health ...
openaire
United Producers Inc. Chapter 11 Restructuring [PDF]
Cooperatives have been used as examples of successful collective action activities. However, member free riding within cooperatives and other collective action groups continues to be a challenge.
Olson, Frayne E.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The Use of Rhyme, Rhythm, and Melody as a Form of Repetition Priming to Aid in Encoding, Storage, and Retrieval of Semantic Memories in Alzheimer’s Patients [PDF]
, 2017 Millions are diagnosed with Alzheimer’s disease annually which can have debilitating effects on patient memory. Thus, finding new ways to help facilitate memory in these patients, especially through non-pharmaceutical means, has become increasingly ...
Plastikwala, Faiz
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Succession planning for organizational stability
Nursing Management, 2021 Christina M, Martin, Kristen, O'Shea
openaire +3 more sources
Institutionalizing planning, enactment and reflection of daily lessons through appropriate organizational restructuring [PDF]
, 2011 Raval, H., McKenney, S., & Pieters, J. (2011). Institutionalizing planning, enactment and reflection of daily lessons through appropriate organizational restructuring.
McKenney, Susan +2 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source