Results 141 to 150 of about 1,051,672 (307)
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Feasibility study of an Integrated Program for Aerospace vehicle Design (IPAD). Volume 1B: Concise review [PDF]
Reports on the design process, support of the design process, IPAD System design catalog of IPAD technical program elements, IPAD System development and operation, and IPAD benefits and impact are concisely reviewed.
Kawaguchi, A. S. +3 more
core +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
United Producers Inc. Chapter 11 Restructuring [PDF]
Cooperatives have been used as examples of successful collective action activities. However, member free riding within cooperatives and other collective action groups continues to be a challenge.
Olson, Frayne E.
core +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
INFORMATION MANAGEMENT ZN GOVERNMENTAL PROCEDURES
Selçuk Üniversitesi Sosyal Bilimler Meslek Yüksekokulu Dergisi, 2014 In the contemporary organizational world, information manage-ment and management information systems are interdependent. Management information Systems (MİS) plays a strategic role in effective information management as well as organizational management ...
Adem Öğüt
doaj
Planning of organizational changes
, 2016 Данная статья показывает важность планирования своей деятельности как руководителя, особенно в периоды проведения активных изменений принципов работы, на всех возможных этапах существования компании, а также проводится логическая связь между конкретными изменениями внутри выбранного процесса не только со смежными направлениями деятельности, но и со ...
openaire +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Time and Organizational Improvisation [PDF]
This paper argues that the apparent contradiction in current conceptualizations of time in organizations (e.g., Chronos vs. Kairos) is only apparent, and that a synthesis between these opposing poles is both possible and desirable.
Crossan, Mary +3 more
core
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source