Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Digital Сompetence of Russian School Teachers
This article presents the results of digital competence study in different types of pedagogical stuff of Russian educational organization (informatics teachers – 140 participants, subject teachers – 145 participants, other categories – 112 participants ...
Soldatova G.U., , Shlyapnikov V.N.,
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conversação entre Abordagens da Estratégia em Organizações: Escolha Estratégica, Cognição e Instituição [PDF]
This paper was written with the objective of checking on the treatment given to the concept of organizational strategy within each of the strategic choice, cognitive and institutional approaches.
Valéria S. da Fonseca +1 more
doaj
The widening gap between production and domestic consumption has led Spain to become the country with the largest volume of wine exports, of which it has a global market share of 20.5%.
Rosa M. Muñoz +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Institutional Pressures and Organizational Characteristics: Implications for Environmental Strategy [PDF]
A broad literature has emerged over the past decades demonstrating that firms' environmental strategies and practices are influenced by stakeholders and institutional pressures.
Michael W. Toffel, Magali A. Delmas
core
Developing an Effective Strategy for Organizational Business Intelligence
Business Intelligence has been adopted across numerous industry sectors where the commensurate benefits have been reported as being significant to those that fall short of expectations.
Hawking, P +3 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Hybrid Strategy and Firm Performance: The Moderating Role of Individual and Technological Ambidexterity [PDF]
It is discussed whether hybrid strategies are beneficial or detrimental to a firm’s performance, because hybrid strategies lead to organizational tensions that arise from the simultaneous pursuit of distinct strategic activities.
Mahr, Ferdinand
core +1 more source

