Results 81 to 90 of about 114,995 (264)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Journal of Applied Science and EngineeringThe corporate innovation landscape has dramatically transformed by the fast adoption of digital technologies, especially the likes of AI and cloud computing.
Likang Qin, Ying Dong, Zeyu Li
doaj +1 more source
Organizational Culture and Its Implementation in the Choice of Strategic Option - Case Study Montenegro [PDF]
Expert Journal of Business and Management, 2014 The topic of this paper is to examine the influence of organizational culture on determination and implementation of the appropriate strategy within the company.
Gordana NIKČEVIĆ
doaj
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Marketing Strategy and Organizational Culture: A Conceptual and Empirical Integration
Marketing Management Journal, 1999 In recent years there has been a growing interest in the concept of organizational culture. While a few of these studies have explicitly discussed the relationship between organizational culture and strategy, to date no study has been published which ...
THOMAS L. BAKER +2 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
As redes sociais como instrumento estratégico para a inteligência competitiva
TransinformaçãoO mapeamento das redes sociais permite a visualização das ligações entre atores no ambiente organizacional, constituindo-se, assim, importante recurso para o compartilhamento da informação e do conhecimento.
Adriana Rosecler Alcará +7 more
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Scandinavian Journal of Work, Environment & HealthOBJECTIVES: The growing care demands of an aging population and a smaller workforce is a big societal problem. Therefore, knowledge on how to organize eldercare work without hampering workers` health is needed.
Christian Tolstrup Wester +5 more
doaj +1 more source
The effect of the coordination between Human Resource Strategy, Human Capital Strategy and Organizational Behavior Strategy on Organizational Performance [PDF]
Muṭāli̒āt-i Mudīriyyat-i Ṣan̒atī, 2007 Introducing strategic human resource management makes human resource management researcher the understood about the relationships between corporate strategy, human capital, human resource strategy and firm performance.
Seyyed Ali Akbar Afjahe, Reza Sepahvand
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source