Results 71 to 80 of about 178,781 (311)
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Systematic Linking of Organizational strategy, HR strategy and Training Strategy Across OLC
, 2011 This study introduces an OLC perspective into SHRM, and develops a framework of strategic alliances of organizational strategy, HR strategy and training strategy across the organizational life cycle.
Chen, Hai-ming; Hung, Shu-tzu
core
Approaches to Knowledge-Based Strategies [PDF]
Revista de Management Comparat International, 2016 Companies face an increasing number of challenges, driven by market pressures, changes in the nature of labour or customers’ needs. In this context, one of the solutions to address these challenges is to develop and implement knowledge based strategies ...
Cristian-Eugen LUCHIAN +2 more
doaj
Academic enjoyment, behavioral engagement, self-concept, organizational strategy and achievement in EFL setting: A multiple mediation analysis. [PDF]
PLoS One, 2022 Kang X, Wu Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Human Resource Planning and Succession Management Strategy for the Public Service 2017
, 2017 The main objective of this strategy document is to provide strategies to address the existing and future succession management challenges. Specific objectives are to:- (i) Institutionalize human resource planning aligned to national and organizational ...
core
BBR: Brazilian Business Review, 2012 The theme of corporate social responsibility (CSR) has not been widely examined in the context of multinationals. This dearth is even greater with respect to subsidiaries, particularly the subject of reverse transfer of practices, that is, the transfer ...
Felipe Mendes Borini +2 more
doaj
The Necessary Thread of Mindfulness Intervention Fidelity Assurance: Enabling an Organizational Strategy to Promote Health Care Professional Well-Being. [PDF]
Glob Adv Health Med, 2021 Klatt MD +4 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source