COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Hospital Organizational Structure and Information Processing: An Entropy Perspective. [PDF]
Entropy (Basel), 2023 Winasti W, Berden H, van Merode F.
europepmc +1 more source
Multibank holding company organizational structure and performance [PDF]
A study of how quantitative measures of the organizational centralization of 62 multibank holding companies relate to holding company profitability.Bank holding companies ; Banking ...
Gary Whalen
core
Unleashing the Power of Data Through Organization: Structure and Connections for Meaning, Learning, and Discovery [PDF]
, 2015 Dagobert Soergel
openalex +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Role of machine and organizational structure in science. [PDF]
PLoS One, 2022 Thu MK, Beppu S, Yarime M, Shibayama S.
europepmc +1 more source
Towards a Model of Designing an Organizational Structure in a Knowledge Based Society [PDF]
The role of the manager in the knowledge society is to lead, in a productive and cost effective manner, a system that is at the crossroads of three worlds: the environment, the human and the organization. To ensure the continuity of the organization, the
Eric Jolivet, Mihai Vărzaru
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The Optimal Design of Fallible Organizations: Invariance of Optimal Decision Criterion and Uniqueness of Hierarchy and Polyarchy Structures [PDF]
We present a general framework to study the project selection problem in an organization of fallible decision-makers. We show that when the organizational size and the majority rule for project acceptance are optimized simultaneously, the optimal quality
Winston T H Koh
core
Perspectives for organization of internal porous structure of loaded elements of optimal topology
, 2020 P. A. Alekhin +2 more
openalex +1 more source