Results 111 to 120 of about 1,384,173 (347)

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Theoretical approaches to the formation of the organizational structure of enterprise management

Ученые записки Российской академии предпринимательства
The activities of economic entities in modern market conditions necessitate the formation of an organizational structure of enterprise management that can meet the goals and objectives of the company, as well as meet the challenges of internal and ...
A. M. Epifanov
doaj   +1 more source

Mapping Current Organizational Structure and Improvement Points of Breast Cancer Multidisciplinary Team Meetings - An Interview Study. [PDF]

J Multidiscip Healthc, 2022
Kočo L, Siebers CCN, Schlooz M, Meeuwis C, Oldenburg HSA, Prokop M, Mann RM.   +6 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Selecting the most suitable organizational structure for hospitals: an integrated fuzzy FUCOM-MARCOS method. [PDF]

Cost Eff Resour Alloc, 2022
Khosravi M, Haqbin A, Zare Z, Shojaei P.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Challenges of the organizational structure of county health network in Iran: findings from a qualitative study. [PDF]

BMC Health Serv Res, 2022
Ghorrabi AT, Kakemam E, Moradi-Joo E, Dehcheshmeh NF.   +3 more
europepmc   +1 more source

Organizational structure and performance in Dutch SMEs [PDF]

The relationship between organisational structure and performance has received little attention over the past few decades, especially in regards to firms with less than 100 employees.
Joris Meijaard, Marco Mosselman, Maryse Brand   +2 more
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

The digital organization transformation (DOT) model: bridging digital transformation and organizational structures in construction firms

Journal of Civil Engineering and Management
Digital transformation is a pathway to improve productivity in the construction sector, but organizational structures still need more adaptation. There are no fully developed models at the level of factors and evidence between organizational structures ...
Cristian C. Osorio-Gómez, Rodrigo F. Herrera, Laura Tupėnaitė, Eugenio Pellicer   +3 more
doaj   +1 more source