Results 51 to 60 of about 1,384,173 (347)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Gestão de Mudanças na Sucessão de uma Empresa Familiar – um Caso Para Ensino
Teoria e Prática em Administração, 2015 BLP is a company in the automotive branch passing through a phase of organizational change, generated by the profile of the new manager and its business model. Name change, implementation of new services and products and mainly team management changes. A
Santos, Adélia Tabaczinski dos +3 more
doaj
Organizational forms and knowledge absorption [PDF]
Industrija, 2016 Managing the entire portion of knowledge in an organization is a challenging task. At the organizational level, there can be enormous quantities of unknown, poorly valued or inefficiently applied knowledge.
Radovanović Nikola, Matović Danijela
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
دراسات العدد الاقتصادي, 2016 The objective of this study is to integrate the lean six sigma method into academic institutions in order to improve the quality of services. Given that professional bureaucracy is the best design for such organizations, it promotes the application of ...
Ahmida FERHAT
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
STRATEGIES AND STRUCTURES OF POLISH SMES
Studia Universitatis Babeş-Bolyai Negotia, 2016 The topic of strategy-structure relation has already been widely discussed in the literature but the research so far concentrated mainly on large enterprises in developed countries while not much research has been done on a sample of small and medium ...
Wioletta MIERZEJEWSKA
doaj +2 more sources
Вестник Дагестанского государственного технического университета: Технические науки, 2019 Objective. The increase in the efficiency of functioning of the (credit) organization due to the realization of procedure of the horizontal, vertical and trend (microscopic) financial analysis based on the formed innovative analytical coefficients system
A. N. Vetrov
doaj +1 more source