Results 91 to 100 of about 2,481,409 (306)
Tourism and HospitalityThe acceptance and effective use of digital technologies constitute a critical prerequisite for the adaptability and sustainability of organizations in tourism and hospitality, particularly in environments characterized by technological acceleration and ...
Ioannis Mihos, Georgios Kokkinis
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
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Frontiers in MedicineBackgroundProgressive liver cirrhosis in pediatric patients characterized by clinical and genetic variability. Infantile cirrhosis caused by biallelic variants in the FOCAD gene is an extremely rare multi-system disorder leading to the progressive liver ...
Ekaterina Nuzhnaya +15 more
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Cadernos de Letras da UFF, 2012 Organizers and program committee for the Intelligent Narrative Technologies 2012 AIIDE ...
openaire +10 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
SocietiesResearch on dishonest behavior within organizational contexts has expanded rapidly in recent years. However, the structural organization of dominant explanatory mechanisms within this literature remains insufficiently clarified.
Soukayna El Majdoubi +3 more
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
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Entrepreneurial bricolage: A systematic literature network analysis and TCCM approach
Scientific AfricanIn recent years, bricolage, often considered an alternative approach to traditional methods of entrepreneurial action, has attracted increasing interest from researchers. This article aims to provide an in-depth overview of the current state of bricolage
Brahim Aaouid +3 more
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