Results 71 to 80 of about 4,744,796 (313)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Entrepreneurial Community Development - Exploring Earned Income Activities and Strategic Alliances for Community Development Nonprofits [PDF]
, 2001 This paper examines social entrepreneurship from a community-development perspective. The target audience is community-development nonprofit organizations.
Ellen Stiefvater
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Misaligned Values in Software Engineering Organizations
, 2018 The values of software organizations are crucial for achieving high performance; in particular, agile development approaches emphasize their importance.
Feldt, Robert +2 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Analyzing the impact of competition policy on economic prosperity in the MENA region (2013–2023)
Social Sciences and Humanities OpenIn the MENA region, where economic disparities and developmental challenges are prevalent, understanding the impact of competition policy is imperative. As these countries undergo significant economic reforms and strive for sustainable development, this ...
Mohammed EL-Khodary +2 more
doaj +1 more source
Next Generation Organizations: 9 Key Traits [PDF]
, 2011 Outlines a vision for impact-driven, business savvy, culturally competent organizations wired for policy advocacy that value continuous learning, shared leadership, ambiguous work-life boundaries, constituents as thought partners, and boards as value ...
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source