Results 41 to 50 of about 273,185 (175)

Stereoselectively fluorinated N-heterocycles: a brief survey

Beilstein Journal of Organic Chemistry, 2013
The stereoselective incorporation of fluorine atoms into N-heterocycles can lead to dramatic changes in the molecules’ physical and chemical properties.
Xiang-Guo Hu, Luke Hunter
doaj   +1 more source

Regioselective 1,4-trifluoromethylation of α,β-unsaturated ketones via a S-(trifluoromethyl)diphenylsulfonium salts/copper system

Beilstein Journal of Organic Chemistry, 2013
Regioselective conjugate 1,4-trifluoromethylation of α,β-unsaturated ketones by the use of shelf-stable electrophilic trifluoromethylating reagents, S-(trifluoromethyl)diphenylsulfonium salts and copper under mild conditions is described. A wide range of
Satoshi Okusu, Yutaka Sugita, Etsuko Tokunaga, Norio Shibata   +3 more
doaj   +1 more source

Enantioselective Benzylation and Allylation of α-Trifluoromethoxy Indanones under Phase-Transfer Catalysis

Molecules, 2019
The organo-catalyzed enantioselective benzylation reaction of α-trifluoromethoxy indanones afforded α-benzyl-α-trifluoromethoxy indanones with a tetrasubstituted stereogenic carbon center in excellent yield with moderate enantioselectivity
Yumeng Liang, Mayaka Maeno, Zhengyu Zhao, Norio Shibata   +3 more
doaj   +1 more source

Reduction of boron diffusion in silicon-germanium by fluorine implantation

, 2004
This paper investigates the effect of a 185 keV, 2.3×1015cm-2 F+ implant on boron thermal diffusion and boron transient enhanced diffusion (TED) in SiGe by characterising the diffusion of a boron marker layer in samples with and without a 288 keV, 6 ...
El Mubarek, H.A.W., Ashburn, P., El Mubarek, H. A W   +2 more
core   +2 more sources

Synthesis of enantiomerically pure (2S,3S)-5,5,5-trifluoroisoleucine and (2R,3S)-5,5,5-trifluoro-allo-isoleucine

Beilstein Journal of Organic Chemistry, 2013
A practical route for the stereoselective synthesis of (2S,3S)-5,5,5-trifluoroisoleucine (L-5-F3Ile) and (2R,3S)-5,5,5-trifluoro-allo-isoleucine (D-5-F3-allo-Ile) was developed.
Holger Erdbrink, Elisabeth K. Nyakatura, Susanne Huhmann, Ulla I. M. Gerling, Dieter Lentz, Beate Koksch, Constantin Czekelius   +6 more
doaj   +1 more source

Joy and Flustration with Organofluorine Compounds – A Fluorous Autobiography

CHIMIA, 2014
An overview is given about our work on fluoro-organic compounds, published or described in PhD theses between 1977 and 2013. After a discussion of structural F-effects and F-tagging applications the material is ordered by the various areas of ...
Dieter Seebach
doaj   +1 more source

The difluoromethylene (CF2) group in aliphatic chains: Synthesis and conformational preference of palmitic acids and nonadecane containing CF2 groups

Beilstein Journal of Organic Chemistry, 2014
The syntheses of palmitic acids and a nonadecane are reported with CF2 groups located 1,3 or 1,4 to each other along the aliphatic chain. Specifically 8,8,10,10- and 8,8,11,11-tetrafluorohexadecanoic acids (6b and 6c) are prepared as well as the singly ...
Yi Wang, Ricardo Callejo, Alexandra M. Z. Slawin, David O’Hagan   +3 more
doaj   +1 more source

Recent advances in transition metal-catalyzed Csp2-monofluoro-, difluoro-, perfluoromethylation and trifluoromethylthiolation

Beilstein Journal of Organic Chemistry, 2013
In the last few years, transition metal-mediated reactions have joined the toolbox of chemists working in the field of fluorination for Life-Science oriented research.
Grégory Landelle, Armen Panossian, Sergiy Pazenok, Jean-Pierre Vors, Frédéric R. Leroux   +4 more
doaj   +1 more source

Multigramme synthesis and asymmetric dihydroxylation of a 4-fluorobut-2E-enoate

Beilstein Journal of Organic Chemistry, 2013
Esters of crotonic acid were brominated on a multigramme scale using a free radical procedure. A phase transfer catalysed fluorination transformed these species to the 4-fluorobut-2E-enoates reproducibly and at scale (48–53%, ca. 300 mmol).
James A. B. Laurenson, John A. Parkinson, Jonathan M. Percy, Giuseppe Rinaudo, Ricard Roig   +4 more
doaj   +1 more source

Elemental fluorine as a valid synthetic reagent [PDF]

, 1994
Chapter I Chapter I reviews the uses of elemental fluorine in selective organic synthesis and its use in the generation of selective electrophilic fluorinating agents.
Skinner, Christopher John
core