Recent Advances in Intramolecular C─N Bond Formation for Pyrrolidine Synthesis
This review highlights synthetic advances (2013–2025) in intramolecular C─N bond formation for constructing the pharmaceutically relevant pyrrolidine core. The review is organized into five methodological clusters: 1) intramolecular alkene/alkyne amination; 2) tandem annulations, which involve C─N bond formation as the key step; 3) nucleophilic ...
Rasma Kroņkalne, Māris Turks
wiley +1 more source
Chemistry of some model compounds related to fluorinated polymers [PDF]
The work described in this thesis is concerned with three areas which are the generation of stable carbocations from saturated model compounds related to poly- vinylidenefluoride, the development of synthetic routes to fluoro-organo-phosphazenes with ...
Odello, Paolo
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A Direct Method to Prepare Zwitterionic Organotrifluoroborates: Ammonium and Sulfonium Derivatives
Organotrifluoroborates find applications in synthesis, diagnostics, and theranostics. This study outlines a one‐step reaction for producing ammonium and sulfonium trifluoroborate zwitterion derivatives. This method achieves satisfactory yields without the need for expensive reagents.
Vanessa Re +6 more
wiley +1 more source
Electrophilic fluorinatíon of ethers and deactivated benzene derivatives [PDF]
Chapter 1 - Chapter 1 provides a literature review of the relevant topics for this thesis in organofluorine chemistry: effect of fluorine as a substituent on the molecule, synthesis of C-F bond from C-H bond using electrophilic reagents with discussions ...
Trmčić, Jelena
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Two‐Stage, Sequential Aryne Carboiodanation Enabled by Mesomeric Priming
Two‐stage, sequential insertion of arynes into the carbon–iodine(III) bond of benziodoxole (BX) compounds is achieved by judicious choice of the BX/aryne pair in the first step, generating a mesomerically activated aryl‐BX primed for a second, discrete aryne insertion. This metal‐free strategy enables programed access to biaryl‐BXs and modular entry to
Shunya Morohashi +3 more
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New methodology for the synthesis of fluorinated aromatics [PDF]
This thesis is concerned with new methodology for the introduction of fluorine atoms, and trifluoromethyl groups into aromatic systems and the following approaches have been adopted: (i) The possibility of selective cleavage of the aryl-silicon bond of ...
Rock, Michael Harold
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Addressing Bottlenecks to Achieve High‐Energy Sodium‐Ion Cells Using Tin Anodes
The challenges in coupling high voltage cathode with Sn‐alloying anode or in anode‐free cell, using glyme based electrolytes to realize high energy Na‐ion cells are reported. Surface protection strategy such as SnO coating on Sn or trapping the parasitic species from poisoning the anode, helps improving the cyclability, with ∼100% capacity retention ...
Parth Desai +11 more
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Free radical reaction of fluorine containing compounds [PDF]
This thesis is concerned with the free-radical addition of oxygen containing compounds of the adducts produced. Free-radical additions of ether compounds to fluoroalkenes have been done by previous workers and the chemistry of some of these adducts has ...
Abu-Nasrieh, Omar M.
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Misconceptions on fluoronium ions and hypervalent fluorine cations [PDF]
In a recent publication (Science, 2013, 340, 57), indirect experimental evidence was presented for the transient generation in solution of a fluorine atom symmetrically bonded to two carbon atoms.
Christe, Karl O. +10 more
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Free radical routes to functional fluorine-containing organic compounds [PDF]
Free radical additions of functional hydrocarbons such as alcohols, aldehydes and ethers to the highly fluorinated alkenes 2H-pentafluoropropene and hexafluoropropene have been studied.
Sneddon, Alan W.A.
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