Results 131 to 140 of about 10,956 (235)
Molecular Stiffening by Macrocycle Clustering
Angewandte Chemie, Volume 137, Issue 22, May 26, 2025.Macrocyclic hosts can remotely rigidify part of a molecule, implying that this part need not be included inside a macrocycle to be stiffened. Here, we show that multiple binding by synthetic hosts CB[7] and CB[8] can selectively rigidify fragments of a tetratopic molecule in water causing a gradual stiffening from the periphery to the core.
Hang Yin +11 more
wiley +2 more sources
Enantioselective Anion‐Binding‐Catalyzed Nucleophilic Addition to 4‐Quinolones
European Journal of Organic Chemistry, EarlyView.The first organocatalytic enantioselective formal 1,4‐addition to 4‐quinolones has been developed. This method relies on chiral triazole‐based anion‐binding catalysis using enol nucleophiles, complementing previous metal catalytic approaches. Moderate to good yields and enantioselectivities were achieved by in situ silylation and formation of a key ...
Martin Aleksiev +2 more
wiley +1 more source
Nature CommunicationsFor mitogen-activated protein kinases (MAPKs) a shallow surface—distinct from the substrate binding pocket—called the D(ocking)-groove governs partner protein binding.
Ádám Levente Póti +17 more
doaj +1 more source
Enantioselective Desymmetrization of Bisphenol Derivatives by Organocatalytic Sulfonylation
European Journal of Organic Chemistry, EarlyView.An efficient organocatalytic strategy involving the desymmetrization–sulfonylation of bisphenols is introduced for the synthesis of chiral 1,1‐diarylalkanes. A chiral thiourea catalyst enables the selective sulfonylation of one hydroxyl group with a sulfonyl chloride in a CHCl3/H2O system under basic conditions, affording the reaction products with ...
Judit Hostalet‐Romero +6 more
wiley +1 more source
Diverse reactivity of maleimides in polymer science and beyond
Polymer International, Volume 74, Issue 4, Page 296-306, April 2025.This mini‐review provides a thorough overview of maleimide chemistry, highlighting its diverse reactivity in polymer and materials science applications. Abstract Maleimides are remarkably versatile functional groups, capable of participating in homo‐ and copolymerizations, Diels–Alder and (photo)cycloadditions, Michael additions, and other reactions ...
Bruce E Kirkpatrick +2 more
wiley +1 more source
Chinese Journal of Chemistry, Volume 43, Issue 13, Page 1553-1559, 1 July 2025.An efficient silylative kinetic resolution of acyclic secondary benzylic alcohols was achieved using chlorosilanes and new axially chiral guanidine catalysts bearing a methoxy group. Comprehensive Summary New chiral guanidine catalysts having axial chirality containing a methoxy group were synthesized. Subsequently, their catalytic ability was examined
Yuki Homma, Takahisa Ikeue, Kenya Nakata
wiley +1 more source
Angewandte Chemie International Edition, Volume 64, Issue 23, June 2, 2025.This interdisciplinary article explores the potential of biodegradable and biobased polymers (BBPs) to address plastic pollution and microplastic generation. It examines feedstock selection, chemical modification, use, and end‐of‐life scenarios, including biodegradation and environmental impact of BBPs.
Sara T. R. Velasquez +5 more
wiley +1 more source
, 2010 International audienceA new method has been developed for the enantioselective synthesis of highly functionalised cyclopentanes bearing up to three stereogenic centres with very high stereoselectivity.
Bonne, Damien +4 more
core +3 more sources
Angewandte Chemie, Volume 137, Issue 20, May 12, 2025.The anti‐ and syn‐selective epoxidation of various α,β‐unsaturated aldehydes is promoted by an engineered variant of 2‐deoxy‐D‐ribose‐5‐phosphate aldolase (DERA), giving rise to various α,β‐epoxy‐aldehydes with excellent enantiopurity (enantiomeric ratio up to 99 : 1). Abstract The enzyme 2‐deoxy‐D‐ribose‐5‐phosphate aldolase (DERA) naturally catalyzes
Hangyu Zhou +5 more
wiley +2 more sources