Results 271 to 280 of about 16,879 (311)

Asymmetric organocatalysis in drug discovery and development for active pharmaceutical ingredients

Expert Opinion on Drug Discovery, 2022
Introduction Over the last 20 years, it has become clear that organocatalysis is the third pillar of catalysis. The low reactivity in the early days of organocatalysis has been overcome with the invention of more efficient catalysts, and by harnessing ...
A. Burke
semanticscholar   +1 more source

Asymmetric organocatalysis: an enabling technology for medicinal chemistry.

Chemical Society Reviews, 2021
The efficacy and synthetic versatility of asymmetric organocatalysis have contributed enormously to the field of organic synthesis since the early 2000s.
Bo Han, Xiang‐Hong He, Yan-Qing Liu, Gu He, Cheng Peng, Jun‐Long Li   +5 more
semanticscholar   +1 more source

Asymmetric Supramolecular Organocatalysis: A Complementary Upgrade to Organocatalysis [PDF]

European Journal of Organic Chemistry, 2017
The recent past has witnessed tremendous growth in the field of asymmetric synthesis through “asymmetric supramolecular organocatalysis (ASO)”. ASO emerges from many interactions between substrates and catalysts: namely substrate–catalyst, catalyst–catalyst and substrate–substrate interactions.
Kengadarane Anebouselvy, Kodambahalli S. Shruthi, Dhevalapally B. Ramachary   +2 more
openaire   +1 more source

Asymmetric Organocatalysis

ChemMedChem, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Stefan, Jaroch, Hilmar, Weinmann, Kirsten, Zeitler   +2 more
openaire   +3 more sources

Bifunctional N-Heterocyclic Carbenes Derived from l-Pyroglutamic Acid and Their Applications in Enantioselective Organocatalysis.

Accounts of Chemical Research, 2020
ConspectusIn nature, enzymes are a powerful medium for the construction of enantiomerically pure chemicals, which always inspires synthetic chemists to explore new catalysts to imitate the enzyme machinery for asymmetric transformations.
Xiang-Yu Chen, Zhong-Hua Gao, Song Ye
semanticscholar   +1 more source

The advent and development of organocatalysis

Nature, 2008
The use of small organic molecules as catalysts has been known for more than a century. But only in the past decade has organocatalysis become a thriving area of general concepts and widely applicable asymmetric reactions. Here I present my opinion on why the field of organocatalysis has blossomed so dramatically over the past decade.
D. MacMillan
semanticscholar   +4 more sources

Atroposelective Organocatalysis

Angewandte Chemie International Edition, 2011
The stereochemical phenomenon that arises from hindered rotation around bonds in nonplanar molecules is termed atropoisomerism.] The presence of a stereogenic axis is the distinct feature in these molecules. One type of atropoisomeric molecule is generated when bulky substituents are placed at the ortho positions of an aryl ring such that there is ...
COZZI, PIER GIORGIO, E. Emer, GUALANDI, ANDREA   +2 more
openaire   +3 more sources

ChemInform Abstract: Organocatalysis in Confined Spaces [PDF]

ChemInform, 2013
AbstractReview: 42 refs.
Gramage-Doria, Rafael, Reek, Joost N. H.
openaire   +5 more sources

Organocatalysis with dendrimers

Chemical Society Reviews, 2012
AbstractReview: 64 refs.
Michel Keller, Michel Keller, Anne-Marie Caminade, Anne-Marie Caminade, Jean-Pierre Majoral, Jean-Pierre Majoral, Armelle Ouali, Armelle Ouali   +7 more
openaire   +4 more sources

Construction of Axially Chiral Compounds via Asymmetric Organocatalysis.

Accounts of Chemical Research, 2018
Axially chiral compounds have received much attention from chemists because of their widespread appearance in natural products, biologically active compounds, and useful chiral ligands in asymmetric catalysis. Because of the importance of this structural
Yong-Bin Wang, B. Tan
semanticscholar   +1 more source