Results 161 to 170 of about 51,205 (219)

The mTOR signaling pathway regulates key steps of mammary gland organoid genesis in a temporal manner. [PDF]

Sci Rep
Lacouture A, Sylla MS, Germain L, Fréville L, Lafront C, Weidmann C, Jobin C, Laplante M, Huot MÉ, Lambert JP, Audet-Walsh É.   +10 more
europepmc   +1 more source

Innate Lymphoid Cells in Tissue Homeostasis and Diseases

MedComm, Volume 7, Issue 5, May 2026.
Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan, Heyang Sun, Chenning Li, Qianya Hong, Shuainan Zhu, Ying Yu, Hao Zhang, Kefang Guo   +7 more
wiley   +1 more source

Genotyping-by-Sequencing Reveals Marker-Based Genome Stability in Tetraploid Clementines for Triploid Breeding. [PDF]

Plants (Basel)
Aleza P, Garcia-Lor A, Mournet P, Navarro L, Ollitrault P.   +4 more
europepmc   +1 more source

The EUROmediCAT Network and Databases: A Resource for Pharmacovigilance in Pregnancy

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 5, May 2026.
ABSTRACT Background The evidence gap relating to the risk of congenital anomalies (CA) associated with first trimester medication exposure in pregnancy is well recognized. Aims We describe the EUROmediCAT network and databases, and the methodological approach to pregnancy pharmacovigilance.
Helen Dolk, Christine Damase‐Michel, Joan Morris, Amanda Neville, Ester Garne, Sue Jordan, Anke Rissmann, Alessio Coi, Deirdre Folan, Dieuwke Broekstra, Jennifer M. Broughan, Lea Bruneau, Clara Cavero‐Carbonell, Elly den Hond, Miriam Gatt, Mika Gissler, Babak Khoshnood, Anna Latos Bielenska, Hedvig Nordeng, Ljubica Odak, Mary O'Mahony, Isabelle Perthus, J. Luke Richardson, Florence Rouget, Joanna Sichitiu, David Tucker, Natalya Zymak‐Zakutnya, Maria Loane   +27 more
wiley   +1 more source

A ‘Genome‐First’ Framework for Next‐Generation Bioinputs: From Functional Mining to Rational Synthetic Microbial Communities

Environmental Microbiology, Volume 28, Issue 5, May 2026.
I propose a ‘genome‐first’ framework to collapse the phenotypic bottleneck in bioinput discovery. By integrating multi‐layered genome mining and reverse ecology, this paradigm enables the rational design of stable synthetic microbial communities for a data‐driven and sustainable agricultural bioeconomy.
Osiel Silva Gonçalves
wiley   +1 more source

Initiation of Direct Shoot Organogenesis in Coconut Using Immature Inflorescence. [PDF]

Plants (Basel)
Kong EYY, Biddle JM, Sisunandar S, Kalaipandian S, Bazrafshan A, Mu Z, Adkins SW.   +6 more
europepmc   +1 more source

Blood‐Based Epigenetic Signatures in Brazilian Males With Alcohol Use Disorder

Addiction Biology, Volume 31, Issue 5, May 2026.
This study represents the first epigenome‐wide association analysis of Alcohol Use Disorder (AUD) in a genetically and culturally diverse Brazilian cohort. Genome‐wide DNA methylation profiling revealed hypomethylation in genes and pathways related to neuronal development, synaptic organization, intracellular signaling and cellular stress responses in ...
Laís da Silva Pereira‐Rufino, Raissa Mazzer de Sino Romano, Regiane Chiavelli Lamim, Rafael Conte, Denise Ribeiro Gobbo, Marcelo Carvalho da Conceição, Vanessa Kiyomi Ota, Lucas Liro, Leslie Domenici Kulikowski, Adriana Marcassa Tucci, Ana Lucia de Moraes Horta, Ana Maria Sebastião, Maria Lucia Oliveira Souza‐Formigoni, João Ricardo Nickenig Vissoci, Alexandre Ferro Aissa, Isabel Cristina Céspedes   +15 more
wiley   +1 more source

Deep Learning and Machine Learning Modeling Identifies Thidiazuron as a Key Modulator of Somatic Embryogenesis and Shoot Organogenesis in <i>Ferula assa-foetida</i> L. [PDF]

Biology (Basel)
Kumari K, Mittal S, Sharma K, Singh S, Upadhyay J, Acharya V, Kadyan V, Yadav SK, Joshi R.   +8 more
europepmc   +1 more source

From Development to Aging: Dynamic Roles of the Thymic Medulla in T Cell Biology

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT The thymic medulla is essential for establishing central tolerance, orchestrating the development of a diverse yet self‐tolerant T cell repertoire, and preventing autoimmunity. This process is primarily mediated through interactions between developing thymocytes and antigen‐presenting cells, including thymic epithelial cells (TECs) and ...
Christina Michalaki, Minahil Sharjeel, Jennifer E. Cowan   +2 more
wiley   +1 more source

Enhancing tomato regeneration and genetic transformation efficiencies via exogenous chemical treatment and the GRF5 gene modulation

Journal of Integrative Plant Biology, Volume 68, Issue 5, Page 1268-1270, May 2026.
Supplementation of Driver and Kuniyuki Walnut Medium with phloroglucinol enhanced regeneration efficiency in tomato tissue culture. Heterologous expression of an Arabidopsis growth‐regulating factor gene, GROWTH‐REGULATING FACTOR5 (GRF5), in tomato improved regeneration and transformation efficiency, suggesting a synergistic effect between ...
Junjie Rong, Lei Zhu, Qingfeng Niu, Jianru Zhao, Fengjuan Chu, Jian‐Kang Zhu, Zhaobo Lang   +6 more
wiley   +1 more source