Results 1 to 10 of about 67 (62)

Evaluation of canine epidermis and keratinocytoids (keratinocytic organoids) by transmission electron microscopy. [PDF]

Vet Dermatol
Background – Skin disease is a common complaint in veterinary medicine. Current models often use live animals. Epidermal organoids (keratinocytoids) are 3D miniature organs created in culture from single epidermal keratinocytes. These keratinocytoids can be used as an alternative to live animal studies to investigate epidermal structures and skin ...
Lui CC, Wiener DJ, Groch KR, Stranahan LW, Heard CR, Armién AG.   +5 more
europepmc   +2 more sources

DECORIN, a triceps-derived myokine, protects sorted β-cells and human islets against chronic inflammation associated with type 2 diabetes. [PDF]

Acta Physiol (Oxf)
Abstract Aim Pancreatic β‐cells are susceptible to inflammation, leading to decreased insulin production/secretion and cell death. Previously, we have identified a novel triceps‐derived myokine, DECORIN, which plays a pivotal role in skeletal muscle‐to‐pancreas interorgan communication.
Langlois A, Cherfan J, Meugnier E, Rida A, Arous C, Peronet C, Hamdard H, Zarrouki B, Wehrle-Haller B, Pinget M, Craige SM, Bouzakri K.   +11 more
europepmc   +2 more sources

Modelos tridimensionais de cultura de células: aproximando o in vitro do in vivo

Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2018
Introdução: Os avanços biotecnológicos em associação com a pressão para substituir a experimentação animal impulsionam o desenvolvimento de modelos in vitro mais fisiológicos e preditivos da resposta in vivo.
Marianna Cavalheiro da Costa, Ana Paula Dantas Nunes de Barros, Rafaela de Assiz Louback, Maria Isabel Doria Rossi   +3 more
doaj   +7 more sources

Nevo Sebáceo de Jadassohn Facial: Uma Apresentação Exuberante

Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2020
O nevo sebáceo de Jadassohn (NSJ) é um hamartoma organoide da pele usualmente observado ao nascimento ou logo após. A localização mais comum é o couro cabeludo, no entanto, pode envolver outras áreas da cabeça e pescoço.
Carolina Fernandes Pereira, Mariana Patriota Naville, Flávia Regina Ferreira, Fernanda da Rocha Gonçalves   +3 more
doaj   +1 more source

Die Linienmuster der Haut und ihre Dermatosen

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 18, Issue 4, Page 341-365, April 2020., 2020
Zusammenfassung Die Kenntnis der Linienmuster der Haut stellt eine Schlüsselkompetenz für jeden Dermatologen dar. Vier Hauptgruppen von Linienmustern sind relevant: Langer‐Linien, Dermatome, Blaschko‐Linien und exogene Muster. Die Langer‐Linien markieren die Richtung der geringsten Spannung der Haut und sind diagnostisch wichtig für einige ...
Sonja Senner, Laurie Eicher, Suzan Nasifoglu, Andreas Wollenberg   +3 more
wiley   +1 more source

Bases experimentales para la identificacion de Leishmania spp. de America por morfometria de amastigotos Experimental basis for the identification of Leishmania spp. of America by morphometry of amastigotes

Memorias do Instituto Oswaldo Cruz, 1982
Estudios morfométricos sobre los amastigotos de dieciocho poblaciones de cuatro aislados pertenecientes a dos especies venezolanas de Leishmania (L. braziliensis y L.
Haideé Urdaneta, J. V. Scorza
doaj   +1 more source

Organoids from colorectal peritoneal metastases as a platform for improving hyperthermic intraperitoneal chemotherapy

BJS (British Journal of Surgery), Volume 106, Issue 10, Page 1404-1414, September 2019., 2019
Organoid technology was used to create a preclinical model for evaluation of hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal metastases from colorectal cancer. Current HIPEC regimens were tested and a novel rational treatment combination of mitomycin C with inhibitors of ATR was investigated.
I. Ubink, A. C. F. Bolhaqueiro, S. G. Elias, D. A. E. Raats, A. Constantinides, N. A. Peters, E. C. E. Wassenaar, I. H. J. T de Hingh, K. P. Rovers, W. M. U. van Grevenstein, M. M. Laclé, G. J. P. L. Kops, I. H. M. Borel Rinkes, O. Kranenburg   +13 more
wiley   +1 more source

Adolescente con una neoformación conformada por dos entidades histológicas independientes: tumor de colisión (Nevo organoide asociado a tricoblastoma)

Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica
El nevo organoide o nevo sebáceo de Jadassohn es una proliferación hamartomosa con diferenciación epidérmica. Es de carácter congénito (usualmente, un mosaicismo genético) pero se manifiesta clínicamente en el transcurso de la infancia, debido a que el ...
Krizzia Chanell Tabora Meza, Raúl Vicente Cabezas Echegoyen, Carmen Alexandra Maza-de Franco, Silvia Anett Mejía-Rodríguez   +3 more
doaj   +1 more source

Photoabbaubare Hydrogele auf Cumarin‐Basis ermöglichen die Zwei‐Photonen kontrollierte subtraktive Biofabrikation bei 300 mm s−1

Angewandte Chemie, Volume 136, Issue 45, November 4, 2024.
Cumarin‐basierte photodegradierbare Hydrogele ermöglichen schnelles, zweiphotonensubtraktives 3D‐Mikrodrucken und lasergesteuerte Zellwachstumsführung auf Abruf, wodurch neue Wege für bio‐medizinische Anwendungen, wie z. B. die raum‐zeitliche Gewebekonstruktion, eröffnet werden.
Wanwan Qiu, Christian Gehre, Jaime Pietrantuono Nepomuceno, Yinyin Bao, Zhiquan Li, Ralph Müller, Xiao‐Hua Qin   +6 more
wiley   +1 more source

Changement d’échelle entre organoïde et organe appliqué au traitement de maladies graves

Entropie, 2023
David Vauris, Jean Claude André
doaj   +1 more source