Results 11 to 20 of about 118 (103)

Die Linienmuster der Haut und ihre Dermatosen

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 18, Issue 4, Page 341-365, April 2020., 2020
Zusammenfassung Die Kenntnis der Linienmuster der Haut stellt eine Schlüsselkompetenz für jeden Dermatologen dar. Vier Hauptgruppen von Linienmustern sind relevant: Langer‐Linien, Dermatome, Blaschko‐Linien und exogene Muster. Die Langer‐Linien markieren die Richtung der geringsten Spannung der Haut und sind diagnostisch wichtig für einige ...
Sonja Senner, Laurie Eicher, Suzan Nasifoglu, Andreas Wollenberg   +3 more
wiley   +1 more source

Organoids are not organs: Sources of variation and misinformation in organoid biology

Stem Cell Reports, 2023
In the past decade, the term organoid has moved from obscurity to common use to describe a 3D in vitro cellular model of a tissue that recapitulates structural and functional elements of the in vivo organ it models. The term organoid is now applied to structures formed as a result of two distinct processes: the capacity for adult epithelial stem cells ...
Kim Bak Jensen, Melissa Helen Little
openaire   +5 more sources

Single organoid RNA-sequencing reveals high organoid-to-organoid variability [PDF]

, 2021
ABSTRACT Over the last decades, organoids have been established from the majority of tissue resident stem and iPS cells. They hold great promise for our understanding of mammalian organ development, but also for the study of disease or even personalized medicine.
Kristin Gehling, Swati Parekh, Farina Schneider, Marcel Kirchner, Vangelis Kondylis, Chrysa Nikopoulou, Peter Tessarz   +6 more
openaire   +1 more source

[Lung organoids].

Medecine sciences : M/S, 2020
As burden of chronic respiratory diseases is constantly increasing, improving in vitro lung models is essential in order to reproduce as closely as possible the complex pulmonary architecture, responsible for oxygen uptake and carbon dioxide clearance. The study of diseases that affect the respiratory system has benefited from in vitro reconstructions ...
Bourguignon, Chloé, Vernisse, Charlotte, Mianné, Joffrey, Fieldes, Mathieu, Ahmed, Engi, Petit, Aurélie, Vachier, Isabelle, Bertrand, Thierry Lavabre, Assou, Said, Bourdin, Arnaud, de Vos, John   +10 more
openaire   +3 more sources

Organoids-on-a-chip

Science, 2019
Recent studies have demonstrated an array of stem cell–derived, self-organizing miniature organs, termed organoids, that replicate the key structural and functional characteristics of their in vivo counterparts. As organoid technology opens up new frontiers of research in biomedicine, there is an emerging need for innovative engineering approaches for ...
Sunghee Estelle Park, Andrei Georgescu, Dongeun Huh   +2 more
openaire   +3 more sources

Bases experimentales para la identificacion de Leishmania spp. de America por morfometria de amastigotos Experimental basis for the identification of Leishmania spp. of America by morphometry of amastigotes

Memorias do Instituto Oswaldo Cruz, 1982
Estudios morfométricos sobre los amastigotos de dieciocho poblaciones de cuatro aislados pertenecientes a dos especies venezolanas de Leishmania (L. braziliensis y L.
Haideé Urdaneta, J. V. Scorza
doaj   +1 more source

Organoids from colorectal peritoneal metastases as a platform for improving hyperthermic intraperitoneal chemotherapy

BJS (British Journal of Surgery), Volume 106, Issue 10, Page 1404-1414, September 2019., 2019
Organoid technology was used to create a preclinical model for evaluation of hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal metastases from colorectal cancer. Current HIPEC regimens were tested and a novel rational treatment combination of mitomycin C with inhibitors of ATR was investigated.
I. Ubink, A. C. F. Bolhaqueiro, S. G. Elias, D. A. E. Raats, A. Constantinides, N. A. Peters, E. C. E. Wassenaar, I. H. J. T de Hingh, K. P. Rovers, W. M. U. van Grevenstein, M. M. Laclé, G. J. P. L. Kops, I. H. M. Borel Rinkes, O. Kranenburg   +13 more
wiley   +1 more source

Patient-Derived Organoids in Precision Medicine: Drug Screening, Organoid-on-a-Chip and Living Organoid Biobank [PDF]

Frontiers in Oncology, 2021
Organoids are in vitro self-assembling, organ-like, three-dimensional cellular structures that stably retain key characteristics of the respective organs. Organoids can be generated from healthy or pathological tissues derived from patients. Cancer organoid culture platforms have several advantages, including conservation of the cellular composition ...
Zilong Zhou, Lele Cong, Xianling Cong
openaire   +3 more sources

Organoids by design

Science, 2019
Organoids are multicellular structures that can be derived from adult organs or pluripotent stem cells. Early versions of organoids range from simple epithelial structures to complex, disorganized tissues with large cellular diversity. The current challenge is to engineer cellular complexity into organoids in a controlled manner that results in ...
Takanori Takebe, James M. Wells
openaire   +3 more sources

Nevo sebáceo de Jadassohn: una rara anomalía epitelial

Duazary
El nevus sebáceo de Jadassohn o nevo organoide, es una malformación hamartomatosa cutánea generalmente benigna, suele presentarse en el momento del nacimiento o poco después, compuesto predominantemente por glándulas sebáceas.
María Alejandra Mendoza-Ospina, Julián Andrés Mendoza-Ospina, Juan Manuel Montaño-Lozada   +2 more
doaj   +1 more source