Results 21 to 30 of about 929 (130)
Etablierung und molekulare Charakterisierung von Mammakarzinom-Organoiden [PDF]
, 2022 Viele Frauen werden im Laufe ihres Lebens mit der Diagnose Mamma-Ca konfrontiert, und trotz bereits weit entwickelter Therapien stirbt noch eine große Anzahl dieser Frauen an ihrer Tumorerkrankung.
Wolf, Franziska
core +1 more source
Bioengineering, 2023 Tissue organoids hold enormous potential as tools for a variety of applications, including disease modeling and drug screening. To effectively mimic the native tissue environment, it is critical to integrate a microvasculature with the parenchyma and stroma. In addition to providing a means to physiologically perfuse the organoids, the microvasculature
Hannah A. Strobel +2 more
openaire +3 more sources
Organoid assessment technologies
Clinical and Translational Medicine, 2023 AbstractDespite enormous advances in the generation of organoids, robust and stable protocols of organoids are still a major challenge to researchers. Research for assessing structures of organoids and the evaluations of their functions on in vitro or in vivo is often limited by precision strategies. A growing interest in assessing organoids has arisen,
Yuyuan Gu +5 more
openaire +3 more sources
Characterization of colon cancer stem cells and their response to treatment with extracts of medical plants [PDF]
, 2019 Il cancro del colon-retto è una delle neoplasie più frequenti, ad alto tasso di mortalità, causato dall’interazione di fattori genetici e ambientali. Parallelamente al modello stocastico, secondo il quale tutte le cellule tumorali (CT) hanno una stessa ...
Iapichino, Anastasia <1989>
core +1 more source
Organoide aus malignem Harnblasengewebe: Etablierung einer Kultivierungsmethode und Vergleich verschiedener Wachstumsbedingungen [PDF]
, 2022 Die Organoidmodell hat in jüngster Vergangenheit Einzug in die Erforschung des Harnblasenkarzinoms gehalten. Muskelinvasive Tumoren der Harnblase sind heutzutage noch mit einer 10-Jahres-Überlebensrate von unter 40 % vergesellschaftet.
Daub, Dominik
core +1 more source
Cold Spring Harbor Perspectives in Medicine, 2018 Oncogenic Kras are genetic dependencies for the majority of pancreatic and colorectal adenocarcinomas; however, much remains to be understood regarding its tropism to these carcinomas. Recently developed organoid technology presents a more representative model culture system for pancreatic and colon epithelial tissues as well as better fostering the ...
Derek, Cheng, David, Tuveson
openaire +2 more sources
Engineering an endocrine Neo-Pancreas by repopulation of a decellularized rat pancreas with islets of Langerhans [PDF]
, 2019 Introduction: Decellularization of pancreata and repopulation of these non-immunogenic matrices with islets and endothelial cells could provide transplantable, endocrine Neo-Pancreata.
Napierala, Hendrik
core +1 more source
Organoids and Colorectal Cancer [PDF]
Cancers, 2021 Organoids were first established as a three-dimensional cell culture system from mouse small intestine. Subsequent development has made organoids a key system to study many human physiological and pathological processes that affect a variety of tissues and organs. In particular, organoids are becoming very useful tools to dissect colorectal cancer (CRC)
Antonio Barbáchano +6 more
openaire +5 more sources
Mikrosatelliteninstabilität in Organoiden aus murinen intestinalen Stammzellen unter Msh2-Defizienz [PDF]
, 2022 Kurzreferat Unter mismatch repair-Defizienz (MMR-D) akkumulieren Mutationen durch die Fehlfunktion eines betroffenen MMR-Gens in Abhängigkeit von der Zeit und können zum Auftreten von kolorektalen Karzinomen (CRC) führen.
Kreutzmann, Tobias
core +2 more sources
Verbesserung der Photorezeptorsegmententwicklung in humanen Retinaorganoiden durch Überexpression des Mikro-RNA Clusters 183/96/182 [PDF]
, 2020 Das Sinnesorgan Auge ist ein wichtiger Bestandteil des menschlichen Lebens. Mit Hilfe des Augenlichtes können Menschen sich in ihrer Umgebung zurechtfinden, orientieren und mit dieser interagieren.
Hawlik, Rainer Christian
core +1 more source