Results 21 to 30 of about 96 (84)
Organoids and Colorectal Cancer [PDF]
Cancers, 2021 Organoids were first established as a three-dimensional cell culture system from mouse small intestine. Subsequent development has made organoids a key system to study many human physiological and pathological processes that affect a variety of tissues and organs. In particular, organoids are becoming very useful tools to dissect colorectal cancer (CRC)
Antonio Barbáchano +6 more
openaire +5 more sources
Medizinrecht, 2020 Organoids are developed from stem cells and serve as three-dimensional model systems for different organs. They have great potential for research and medicine, but also raise philosophical, ethical and legal questions which have rarely been discussed in Germany so far.
openaire +3 more sources
Angewandte Chemie, Volume 136, Issue 45, November 4, 2024.Cumarin‐basierte photodegradierbare Hydrogele ermöglichen schnelles, zweiphotonensubtraktives 3D‐Mikrodrucken und lasergesteuerte Zellwachstumsführung auf Abruf, wodurch neue Wege für bio‐medizinische Anwendungen, wie z. B. die raum‐zeitliche Gewebekonstruktion, eröffnet werden.
Wanwan Qiu +6 more
wiley +1 more source
Life Science Alliance, 2022 Over the last decades, organoids have been established from most of the tissue-resident stem and iPS cells. They hold great promise for our understanding of mammalian organ development, but also for the study of disease or even personalised medicine. In recent years, several reports hinted at intraculture organoid variability, but a systematic analysis
Kristin Gehling +6 more
openaire +3 more sources
Current Opinion in Biomedical Engineering, 2020 Recent advances in biofabrication technologies, such as cell culture systems, and biomaterials have led to the development of three-dimensional (3D) cell culture platforms, such as tumor organoids. Tumor organoids are more physiologically accurate to the in vivo system, which they are intended to model, compared with traditional 2D cancer cell culture ...
Anthony Dominijanni +5 more
openaire +3 more sources
Standard: Human intestinal organoids
Cell Regeneration, 2023 AbstractOrganoids have attracted great interest for disease modelling, drug discovery and development, and tissue growth and homeostasis investigations. However, lack of standards for quality control has become a prominent obstacle to limit their translation into clinic and other applications.
Yalong Wang +25 more
openaire +3 more sources
Engineering Organoid Vascularization [PDF]
Frontiers in Bioengineering and Biotechnology, 2019 The development of increasingly biomimetic human tissue analogs has been a long-standing goal in two important biomedical applications: drug discovery and regenerative medicine. In seeking to understand the safety and effectiveness of newly developed pharmacological therapies and replacement tissues for severely injured non-regenerating tissues and ...
Grebenyuk, Sergei, Ranga, Adrian
openaire +3 more sources
Acta Dermato-Venereologica, 1980 Abstract is not ...
K, Kuokkanen, M, Koivikko, M, Alavaikko
openaire +2 more sources
Science, 2019 Organoids are multicellular structures that can be derived from adult organs or pluripotent stem cells. Early versions of organoids range from simple epithelial structures to complex, disorganized tissues with large cellular diversity. The current challenge is to engineer cellular complexity into organoids in a controlled manner that results in ...
Takanori Takebe, James M. Wells
openaire +3 more sources
Organoids: Avatars for Personalized Medicine
The Keio Journal of Medicine, 2019 Stem cells are the foundation of all mammalian life. Stem cells build and maintain our bodies throughout life. Two types of stem cells are discerned.1) Embryonic stem cells (ES cells) are briefly present in the early human or mouse embryo, a few days after fertilization.
openaire +4 more sources