Results 31 to 40 of about 929 (130)

Humane neuromuskuläre Organoide - Anwendung und Perspektive [Human neuromuscular organoids - Application and perspective] [PDF]

open access: yes, 2021
Organoids are miniature, organ-like structures derived from stem cells. While techniques for developing organoids for different tissues have advanced in the past decade, it has remained a challenge to simultaneously grow two different tissues into a ...
Faustino Martins, J.M.   +2 more
core   +1 more source

Modellierung von Aktin-assoziierten kortikalen Malformationen in zerebralen Organoiden [PDF]

open access: yes, 2023
Hintergrund: Das Baraitser-Winter-Zerebro-Fronto-Faziale-Syndrom (BWCFF-S) gehört mit einer Prävalenz von 1:1.000.000 zu den sehr seltenen genetischen Krankheiten und wird durch Missense-Mutationen in den Genen ACTB und ACTG1, die die zytoplasmatischen ...
Niehaus, Indra
core   +1 more source

Quiste odontogénico calcificante asociado con odontoma complejo: presentación de un caso y revisión bibliográfica [PDF]

open access: yes, 2005
Se presenta un caso de quiste odontogénico calcificante asociado con odontoma (QOCaO) y con un canino permanente incluido en maxilar superior, en un paciente varón de 19 años.
Avellá Vecino, F.J.   +4 more
core   +1 more source

Sarcoma alveolar de partes blandas: aportación de un caso [PDF]

open access: yes, 1993
Se presenta el caso de un sarcoma alveolar de partes blandas de 5 años de evolución, localizado en el tercio proximal del muslo izquierdo, en una mujer de 32 años.
Aznar Aznarez, J. Mª   +4 more
core  

Wirkmechanismus eines SIRT6-Modulators in intestinalen Epithelzellen bei chronisch-entzündlichen Darmerkrankungen [PDF]

open access: yes, 2023
Intestinale Epithelzellen bilden eine wichtige Schutzschicht des Darms gegenüber Pathogenen aus der Umwelt und sind gleichzeitig in der Lage, wichtige Nährstoffe aus dem Darmlumen zu resorbieren.
Vögele, Anna-Lena
core   +2 more sources

RNA-sequencing of single cholangiocyte-derived organoids reveals high organoid-to organoid variability

open access: yesLife Science Alliance, 2022
Over the last decades, organoids have been established from most of the tissue-resident stem and iPS cells. They hold great promise for our understanding of mammalian organ development, but also for the study of disease or even personalised medicine. In recent years, several reports hinted at intraculture organoid variability, but a systematic analysis
Kristin Gehling   +6 more
openaire   +3 more sources

Bioengineered tumor organoids

open access: yesCurrent Opinion in Biomedical Engineering, 2020
Recent advances in biofabrication technologies, such as cell culture systems, and biomaterials have led to the development of three-dimensional (3D) cell culture platforms, such as tumor organoids. Tumor organoids are more physiologically accurate to the in vivo system, which they are intended to model, compared with traditional 2D cancer cell culture ...
Anthony Dominijanni   +5 more
openaire   +3 more sources

Organoide - Die deutsche Rechtslage [PDF]

open access: yes, 2020
In seinem Beitrag stellt Herr Taupitz die deutsche Rechtslage zu Organoiden vor. Auch wenn es kein eigenes Gesetz zur Regulierung dieses neuen Bereiches gibt, sind doch viele bestehende Gesetze auch in diesem Kontext ...
Taupitz, Jochen
core  

Standard: Human intestinal organoids

open access: yesCell Regeneration, 2023
AbstractOrganoids have attracted great interest for disease modelling, drug discovery and development, and tissue growth and homeostasis investigations. However, lack of standards for quality control has become a prominent obstacle to limit their translation into clinic and other applications.
Yalong Wang   +25 more
openaire   +3 more sources

Engineering Organoid Vascularization [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
The development of increasingly biomimetic human tissue analogs has been a long-standing goal in two important biomedical applications: drug discovery and regenerative medicine. In seeking to understand the safety and effectiveness of newly developed pharmacological therapies and replacement tissues for severely injured non-regenerating tissues and ...
Grebenyuk, Sergei, Ranga, Adrian
openaire   +3 more sources

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