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Les organoïdes de prostate: un outil prometteur pour cribler des perturbateurs endocriniens
Annales d'Endocrinologie, 2021L’identification de perturbateurs endocriniens (PE) en amont de leurs effets nefastes sanitaires est complexe, notamment lorsqu’elle integre les effets a faibles doses et les effets cocktails.
E. Bokobza +7 more
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Developmental Cell
Organoids, 3D in vitro structures derived from embryonic or adult stem cells, offer powerful models for studying tissue patterning, development, morphogenesis, organ physiology, and disease. These systems replicate biological processes, such as cell differentiation, symmetry breaking, and tissue organization, while revealing species-specific ...
Vanessa, Weichselberger +5 more
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Organoids, 3D in vitro structures derived from embryonic or adult stem cells, offer powerful models for studying tissue patterning, development, morphogenesis, organ physiology, and disease. These systems replicate biological processes, such as cell differentiation, symmetry breaking, and tissue organization, while revealing species-specific ...
Vanessa, Weichselberger +5 more
openaire +2 more sources
Nature Reviews Cancer, 2019
Neal et al. have successfully established patient-derived organoids of tumour epithelia retaining native immune cells, thereby recapitulating tumour microenvironment diversity and enabling immuno-oncology studies.
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Neal et al. have successfully established patient-derived organoids of tumour epithelia retaining native immune cells, thereby recapitulating tumour microenvironment diversity and enabling immuno-oncology studies.
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Science, 2017
Hans Clevers pioneered lab-built mini-organs that can serve as models of ...
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Hans Clevers pioneered lab-built mini-organs that can serve as models of ...
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Organoids in Tissue Transplantation
2021Improvements in stem cell-based research and genetic modification tools enable stem cell-based tissue regeneration applications in clinical therapies. Although inadequate cell numbers in culture, invasive isolation procedures, and poor survival rates after transplantation remain as major challenges, cell-based therapies are useful tools for tissue ...
Derya, Sağraç +5 more
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Advances in Organoid Technology: A Focus on Corneal Limbal Organoids
Stem Cell Reviews and ReportsOrganoid technology provides a versatile platform for simulating organogenesis, investigating disease pathogenesis, and exploring therapeutic interventions. Among various types of organoids that have been developed, corneal limbal organoids, the three-dimensional miniaturized corneas which are derived from either pluripotent stem cells or limbal ...
Chuwei Lu, Qihua Le
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