Results 71 to 80 of about 101 (86)
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Cryopreservation of Organoids

Cryoletters, 2023
Organoids represent indispensable opportunities for biomedicine, including drug discovery, cancer biology, regenerative and personalised medicine or tissue and organ transplantation. However, the lack of optimised preservation strategies limits the wide use of organoids in research or clinical fields.
O, Rogulska, J, Havelkova, Y, Petrenko
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Generation of Organoids and Analysis of Ferroptosis in Organoids

2023
Ferroptosis is a unique form of iron-dependent cell death induced by lipid peroxidation and subsequent plasma membrane rupture, which sets it apart from other types of regulated cell death. Ferroptosis has been linked to a diverse range of biological processes, such as aging, immunity, and cancer. Organoids, on the other hand, are three-dimensional (3D)
Wenxin, Li   +4 more
openaire   +2 more sources

Commercialization of Organoids

Trends in Molecular Medicine, 2020
Organoids have been successfully exploited for drug screening, disease modeling, pathogenesis, and regenerative medicine. Herein, we discuss the progress achieved in the commercialization of organoids in the last few years. We further elaborate on the concept of organoid biobank and highlight ethical and regulatory issues surrounding organoid research ...
Deepak, Choudhury   +2 more
openaire   +2 more sources

Biophysics of organoids

Developmental Cell
Organoids, 3D in vitro structures derived from embryonic or adult stem cells, offer powerful models for studying tissue patterning, development, morphogenesis, organ physiology, and disease. These systems replicate biological processes, such as cell differentiation, symmetry breaking, and tissue organization, while revealing species-specific ...
Vanessa, Weichselberger   +5 more
openaire   +2 more sources

Organoid 2.0

Nature Reviews Cancer, 2019
Neal et al. have successfully established patient-derived organoids of tumour epithelia retaining native immune cells, thereby recapitulating tumour microenvironment diversity and enabling immuno-oncology studies.
openaire   +2 more sources

The organoid architect

Science, 2017
Hans Clevers pioneered lab-built mini-organs that can serve as models of ...
openaire   +2 more sources

Organoids

Nature Biotechnology
Boon-Cher Goh   +2 more
  +6 more sources

Organoids

Nature Biotechnology, 2021
openaire   +2 more sources

Advances in Organoid Technology: A Focus on Corneal Limbal Organoids

Stem Cell Reviews and Reports
Organoid technology provides a versatile platform for simulating organogenesis, investigating disease pathogenesis, and exploring therapeutic interventions. Among various types of organoids that have been developed, corneal limbal organoids, the three-dimensional miniaturized corneas which are derived from either pluripotent stem cells or limbal ...
Chuwei Lu, Qihua Le
openaire   +2 more sources

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