Broadly expressed genes outperformed brain‐enriched neural targets as RNAi candidates in Halyomorpha halys. Microinjection of dsRNA targeting alpha‐soluble NSF attachment protein (Asnap) or Ras opposite protein (Rop) caused strong feeding suppression and near‐complete mortality, identifying them as promising targets for future oral or spray‐based RNAi ...
Nirakar Panda +2 more
wiley +1 more source
Intentional Large-Volume Diazinon Ingestion Complicated by Seizure and Acute Respiratory Failure: A Case Report. [PDF]
Alnuaimi KH +4 more
europepmc +1 more source
ABSTRACT Objective Many antidotes are relatively rare‐use, indication‐specific medicines with a variable evidence base. In Aotearoa New Zealand, there are no national statistics available on their use. This study aimed to characterize the numbers of cases and advice provided by the Aotearoa New Zealand National Poisons Centre (NZNPC) on the use of true
Eeva‐Katri Kumpula, William Boroughf
wiley +1 more source
Detection of Terbufos (Organophosphate) Intoxication in Necrophagous Larvae Using Biospectroscopy (ATR-FTIR) with Multivariate Selection Algorithms. [PDF]
Jales JT +5 more
europepmc +1 more source
Dualsteric and dual‐acting modulation of muscarinic receptors by antagonist KH‐5
Abstract Background and purpose Muscarinic acetylcholine receptors are key therapeutic targets, and ligands engaging both orthosteric and allosteric sites may offer improved selectivity and efficacy. Here, we investigated whether the muscarinic antagonist KH‐5 acts as a dualsteric antagonist and defined its mode of interaction with muscarinic receptors.
Alena Janoušková‐Randáková +3 more
wiley +1 more source
<i>Drosophila</i> as a model in organophosphate toxicology. [PDF]
Tkachuk M, Matiytsiv N.
europepmc +1 more source
ABSTRACT Pediatric cancer is a significant cause of morbidity and mortality in children. The etiologies of pediatric cancer are largely unknown, but environmental pesticide exposures are likely to contribute. Chronic low‐dose exposure to pesticide mixtures through drinking water is a growing concern in agricultural communities.
Grace N. VanDeSteeg +4 more
wiley +1 more source
A tale of three mimickers: Amitraz, fipronil, and 2,4-dichlorophenoxyacetic acid poisoning confounding organophosphate toxicity. [PDF]
Bhimani KS +4 more
europepmc +1 more source
Recent Applications of Propylene Carbonate as a Solvent in Sustainable Organic Synthesis
This review evaluates propylene carbonate (PC) as a non‐toxic green solvent in organic synthesis, highlighting its performance in key reactions including cross‐couplings, asymmetric hydrogenations, peptide synthesis and biocatalysis. Across these processes, PC delivers yields comparable to conventional and alternative green solvents.
Laura G. Aguilar‐Sanchez +1 more
wiley +1 more source
Childhood and adolescent poisoning: a prospective analysis from the largest poison control centre. [PDF]
Soomar SM +9 more
europepmc +1 more source

