Results 11 to 20 of about 87,905 (291)

A companion to the preclinical common data elements for phenotyping seizures and epilepsy in rodent models. A report of the TASK3‐WG1C: Phenotyping working group of the ILAE/AES joint translational task force

Epilepsia Open, EarlyView., 2022
Abstract Epilepsy is a heterogeneous disorder characterized by spontaneous seizures and behavioral comorbidities. The underlying mechanisms of seizures and epilepsy across various syndromes lead to diverse clinical presentation and features. Similarly, animal models of epilepsy arise from numerous dissimilar inciting events.
Melissa Barker‐Haliski, Julika Pitsch, Aristea S. Galanopoulou, Rüdiger Köhling   +3 more
wiley   +1 more source

Chlorpyrifos Disrupts Acetylcholine Metabolism Across Model Blood-Brain Barrier

Frontiers in Bioengineering and Biotechnology, 2021
Despite the significant progress in both scientific understanding and regulations, the safety of agricultural pesticides continues to be called into question.
Dusty R. Miller, Ethan S. McClain, James N. Dodds, James N. Dodds, James N. Dodds, James N. Dodds, James N. Dodds, Andrzej Balinski, Andrzej Balinski, Andrzej Balinski, Andrzej Balinski, Andrzej Balinski, Jody C. May, Jody C. May, Jody C. May, Jody C. May, Jody C. May, John A. McLean, John A. McLean, John A. McLean, John A. McLean, John A. McLean, David E. Cliffel, David E. Cliffel, David E. Cliffel   +24 more
doaj   +1 more source

Accidental poisoning with aluminum phosphide presenting with excessive cholinergic symptoms with response to atropine: A case report

Avicenna Journal of Medicine, 2021
Accidental poisoning in children, though underreported in our environment, is common and could prove fatal. It is important to identify the primary chemical agent that is responsible for the poisoning.
Abubakar Muhammad Shakur, Nuhu Abubakar Garba, Ibrahim Ahmadu, Daniel Apollos, Mustafa O Asani, Ibrahim Aliyu   +5 more
doaj   +1 more source

Organophosphate pesticides and new-onset diabetes mellitus: From molecular mechanisms to a possible therapeutic perspective

World Journal of Diabetes, 2021
Organophosphate is a commonly used pesticide in the agricultural sector. The main action of organophosphate focuses on acetylcholinesterase inhibition, and it therefore contributes to acute cholinergic crisis, intermediate syndrome and delayed ...
Y. Chung, Yi-Chou Hou, I. Wang, K. Lu, T. Yen   +4 more
semanticscholar   +1 more source

Prognostic Factors of Organophosphate Poisoning Between the Death and Survival Groups

Kaohsiung Journal of Medical Sciences, 2007
In this prospective case series study, we consider the different factors between death and survival groups of organophosphate poisoning. Patients in tertiary-care medical center who had been exposed to organophosphate were included in the study ...
Tzeng-Jih Lin, Donald-D Jiang, Hon-Man Chan, Dong-Zong Hung, Hong-Ping Li   +4 more
doaj   +1 more source

Sequence variation and regulatory variation in acetylcholinesterase genes contribute to insecticide resistance in different populations of Leptinotarsa decemlineata

Ecology and Evolution, 2021
Although insect herbivores are known to evolve resistance to insecticides through multiple genetic mechanisms, resistance in individual species has been assumed to follow the same mechanism.
Aigi Margus, Saija Piiroinen, Philipp Lehmann, Alessandro Grapputo, Leona Gilbert, Yolanda H. Chen, Leena Lindström   +6 more
doaj   +1 more source

A rare case of Organophosphate poisoning with toxic encephalopathy

Journal of Integrated Health Sciences, 2016
Organophosphate compounds (OPCs) are used mostly as pesticides. In India, Organophosphate poisoning occurs most commonly due to suicidal ingestion. Depending on the type and the dose of the organophosphate compound exposure some clinical syndromes, such ...
S K Tilara, J V Solanki, P A Bhatt
doaj   +1 more source

Losing the ‘arms race’: multiresistant salmon lice are dispersed throughout the North Atlantic Ocean

Royal Society Open Science, 2021
Nothing lasts forever, including the effect of chemicals aimed to control pests in food production. As old pesticides have been compromised by emerging resistance, new ones have been introduced and turned the odds back in our favour.
Helene Børretzen Fjørtoft, Frank Nilsen, Francois Besnier, Anne Stene, Ann-Kristin Tveten, Pål Arne Bjørn, Vidar Teis Aspehaug, Kevin Alan Glover   +7 more
doaj   +1 more source

Organophosphate esters in indoor dust from 12 countries: Concentrations, composition profiles, and human exposure [PDF]

, 2019
A total of 20 organophosphate triesters (OPEs), including seven alkyl-OPEs, three chlorinated (Cl)-OPEs, seven aryl-OPEs, and three oligomeric-OPEs were measured in 341 house dust samples collected from 12 countries during the period 2010-2014. OPEs were
문효방
core   +1 more source

Quantitative Structure-Activity Relationship Analysis of Organophosphate Insecticides Using Electronic and Molecular Parameters

Makara Journal of Science, 2017
Quantitative Structure-Activity Relationship (QSAR) analysis of organophosphate derivatives, and their insecticide activities, was performed using electronic and molecular parameters.
Yari Mukti Wibowo, Mudasir Mudasir, Harno Dwi Pranowo   +2 more
doaj   +1 more source