Results 21 to 30 of about 55,372 (251)

Chlorpyrifos Disrupts Acetylcholine Metabolism Across Model Blood-Brain Barrier

Frontiers in Bioengineering and Biotechnology, 2021
Despite the significant progress in both scientific understanding and regulations, the safety of agricultural pesticides continues to be called into question.
Dusty R. Miller, Ethan S. McClain, James N. Dodds, James N. Dodds, James N. Dodds, James N. Dodds, James N. Dodds, Andrzej Balinski, Andrzej Balinski, Andrzej Balinski, Andrzej Balinski, Andrzej Balinski, Jody C. May, Jody C. May, Jody C. May, Jody C. May, Jody C. May, John A. McLean, John A. McLean, John A. McLean, John A. McLean, John A. McLean, David E. Cliffel, David E. Cliffel, David E. Cliffel   +24 more
doaj   +1 more source

Geospatial model of organophosphate insecticide residues in shallot land in Wanasari Sub-district, Brebes Regency, Central Java Province, Indonesia [PDF]

E3S Web of Conferences, 2020
Organophosphates are a group of chemicals that are still allowed to be used in Indonesia and much preferred by most farmers. Excessive usage of organophosphate is expected to contaminate the soil, water, plants, the environment and humans.
Indratin, Arief Budihardjo Mochamad, Helmi Muhammad   +2 more
doaj   +1 more source

Inhibition of neurite outgrowth in differentiating mouse N2a neuroblastoma cells by phenyl saligenin phosphate: Effects on MAP kinase (ERK 1/2) activation, neurofilament heavy chain phosphorylation and neuropathy target esterase activity [PDF]

, 2006
Sub-lethal concentrations of the organophosphate phenyl saligenin phosphate (PSP) inhibited the outgrowth of axon-like processes in differentiating mouse N2a neuroblastoma cells (IC50 2.5 μM).
Abou-Donia, Abou-Donia, Alan J. Hargreaves, Barber, Barber, Brunet, Casida, Chambers, Denizot, Ehrich, El-Fawal, Eto, Flaskos, Flaskos, Forshaw, Fowler, Glynn, Glynn, Gupta, Hatch, Henschler, Ian C. Coutts, James, Jensen, John Flaskos, Johnson, Johnson, Johnson, Jortner, Jortner, Keilbaugh, Laemmli, Lee, Li, Lowry, Magdalini Sachana, Mary Bountouri, Maxine J. Fowler, Nixon, Nomeir, Nomeir, Nostrandt, Nostrandt, Paul Glynn, Perron, Rosenstock, Schmuck, Sharma, Song, Suwita, Towbin, Van Teinhoven, Veeranna, Veronesi, W. Graham McLean, Wayne Harris, Zhao   +56 more
core   +1 more source

Quantitative Structure-Activity Relationship Analysis of Organophosphate Insecticides Using Electronic and Molecular Parameters

Makara Journal of Science, 2017
Quantitative Structure-Activity Relationship (QSAR) analysis of organophosphate derivatives, and their insecticide activities, was performed using electronic and molecular parameters.
Yari Mukti Wibowo, Mudasir Mudasir, Harno Dwi Pranowo   +2 more
doaj   +1 more source

Evaluation of acetylcholine esterase activity in the blood of workers exposed [PDF]

Kirkuk Journal of Science, 2013
Introduction:Organophosphate and carbamate insecticides pose major environmental pollution problems and health hazards to people and animals. These insecticides inhibit cholinesterase (ChE) activity in the nervous tissues and neuromuscular junctions.
Aydin S. Ahmed
doaj   +1 more source

Pharmacological Blockade of the Calcium Plateau Provides Neuroprotection Following Organophosphate Paraoxon Induced Status Epilepticus in Rats [PDF]

, 2016
Organophosphate (OP) compounds which include nerve agents and pesticides are considered chemical threat agents. Currently approved antidotes are crucial in limiting OP mediated acute mortality.
Ajdacic-Gross, Bajgar, Baker, Barkus, Battaglia, Bengtson, Beverly A. Huang, Campbell, Chemical Hazards Emergency Medical Management, de Araujo Furtado, DeLorenzo, DeLorenzo, Deshpande, Deshpande, Deshpande, Deshpande, Deshpande, Faure, Filbert, Grynkiewicz, Haley, Helmstaedter, Hood, Konradsen, Kristin F. Phillips, Laxmikant S. Deshpande, Li, Li, Loubinoux, Nagarkatti, Neligan, Niebauer, Peng, Phillips, Raghupathi, Raza, Robert E. Blair, Robert J. DeLorenzo, Rod, Savage, Sellstrom, Than, Truitt, Tuovinen   +43 more
core   +2 more sources

Sequence variation and regulatory variation in acetylcholinesterase genes contribute to insecticide resistance in different populations of Leptinotarsa decemlineata

Ecology and Evolution, 2021
Although insect herbivores are known to evolve resistance to insecticides through multiple genetic mechanisms, resistance in individual species has been assumed to follow the same mechanism.
Aigi Margus, Saija Piiroinen, Philipp Lehmann, Alessandro Grapputo, Leona Gilbert, Yolanda H. Chen, Leena Lindström   +6 more
doaj   +1 more source

Intramuscular pyrethroid with organophosphorus (cypermethrine 3% + quinolphos 20%) mixed poisoning, its clinical presentation and management

Journal of Family Medicine and Primary Care, 2020
Organophosphorus compounds are absorbed by any route including intramuscular injection. Pyrethroid compounds are less toxic for human but in combination with organophosphates, its toxic effect potentiates due to inhibition of its metabolism. In this case
Mohammad Firoz Nizami, Chandra B Sharma, Bhoopendra Singh, Rishi T Guria   +3 more
doaj   +1 more source

Atomic layer deposition of aluminum phosphate based on the plasma polymerization of trimethyl phosphate [PDF]

, 2014
Aluminum phosphate thin films were deposited by plasma-assisted atomic layer deposition (ALD) using a sequence of trimethyl phosphate (TMP, Me3PO4) plasma, O-2 plasma, and trimethylaluminum (TMA, Me3Al) exposures.
Detavernier, Christophe, Dobbelaere, Thomas, Roy, Amit Kumar, Vereecken, Philippe   +3 more
core   +1 more source

Plasma Cholinesterase Levels of Nepalese Farmers Following Exposure to Organophosphate Pesticides

Environmental Health Insights, 2017
Background: Farmers in developing countries use highly toxic organophosphate pesticides. Thus, the aim of this study was to compare plasma cholinesterase (PChE) enzyme activity before and after exposure to organophosphate pesticides in a real-life ...
Dinesh Neupane, Erik Jørs, Lars Peter Andreas Brandt   +2 more
doaj   +1 more source