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Development and validation of a prediction model for in-hospital mortality in older adults with acute poisoning. [PDF]
Li K, Ye J, Tang Y, Chen L, Lu Z.
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Comparative analysis of ingestion assessment methods in paraquat-poisoned patients. [PDF]
Jin YL, Meng N, Wang M, Gao HB, Tian YP.
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Acute organophosphorus poisoning
Clinica Chimica Acta, 2014Acute organophosphorus poisoning continues to be a detrimental problem and a potential cause of mortality especially in developing countries. Inhibition of acetylcholinesterase enzyme is the main mechanism of toxicity of such pesticides and measurement of acetylcholinesterase activity is the commonly used laboratory diagnosis approved for the purpose ...
Sheemona, Chowdhary +2 more
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Organophosphorus and carbamate insecticide poisoning
2015Both organophosphorus (OP) and carbamate insecticides inhibit acetylcholinesterase (AChE), which results in accumulation of acetylcholine (ACh) at autonomic and some central synapses and at autonomic postganglionic and neuromuscular junctions. As a consequence, ACh binds to, and stimulates, muscarinic and nicotinic receptors, thereby producing ...
Allister, Vale, Marcello, Lotti
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PHYSIOLOGICAL EVENTS IN ORGANOPHOSPHORUS POISONING
Canadian Journal of Biochemistry and Physiology, 1959Null
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Organophosphorus pesticide poisoning
The Netherlands Journal of Medicine, 2008Self-poisoning with organophosphate pesticides is a major health problem world-wide. Through the inhibition of acetylcholinesterase, organophosphorus poisoning is characterised by the clinical picture of acute cholinergic crisis. Other manifestations are the intermediate neurotoxic syndrome and delayed polyneuropathy.In the Western world, the ...
Aardema, H. +5 more
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Organophosphorus poisoning (acute).
BMJ clinical evidence, 2016Acetylcholinesterase inhibition by organophosphorus pesticides or organophosphate nerve agents can cause acute parasympathetic system dysfunction, muscle weakness, seizures, coma, and respiratory failure. Prognosis depends on the dose and relative toxicity of the specific compound, as well as pharmacokinetic factors.We conducted a systematic review and
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Organophosphorus insecticide poisoning.
BMJ clinical evidence, 2018Acetylcholinesterase inhibition by organophosphorus insecticides can cause acute parasympathetic system dysfunction, muscle weakness, seizures, coma, and respiratory failure. Prognosis depends on the dose and relative toxicity of the specific compound, as well as pharmacokinetic factors.We conducted a systematic overview, aiming to answer the following
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